# IBRN holdings and overlap

iShares Neuroscience and Healthcare ETF, Health Care, iShares.

Canonical page: https://tickerinside.com/etf/ibrn/
Holdings from the issuer file published 2026-09-03. Prices through 2026-09-04.
Licence: CC BY 4.0, attribution to TickerInside. Measurements, not investment advice.

## Largest positions, issuer file of 2026-09-03

| Rank | Ticker | Company | Weight |
| --- | --- | --- | --- |
| 1 | PRAX | Praxis Precision Medicines | 5.23% |
| 2 | DNTH | Dianthus Therapeutics Inc | 5.02% |
| 3 | SRRK | Scholar Rock Holding | 4.73% |
| 4 | ACAD | Acadia Pharmaceuticals | 4.71% |
| 5 | ARWR | Arrowhead Pharmaceuticals | 4.43% |
| 6 | ARGX | Argenx SE ADR | 4.43% |
| 7 | XENE | Xenon Pharmaceuticals | 4.37% |
| 8 | BIIB | Biogen | 4.3% |
| 9 | ALKS | Alkermes | 4.1% |
| 10 | PTCT | PTC Therapeutics | 3.77% |
| 11 | NBIX | Neurocrine Biosciences | 3.62% |
| 12 | DNLI | Denali Therapeutics | 3.39% |
| 13 | AXSM | Axsome Therapeutics | 3.36% |
| 14 | DYN | Dyne Therapeutics | 3.29% |
| 15 | EWTX | Edgewise Therapeutics | 3.29% |
| 16 | 326030 | SK Biopharmaceuticals Ltd | 2.48% |
| 17 | AXGN | Axogen | 2.43% |
| 18 | SUPN | Supernus Pharmaceuticals | 2.39% |
| 19 | SRPT | Sarepta Therapeutics | 2.32% |
| 20 | BHVN | Biohaven | 1.99% |
| 21 | HLUN B | H. Lundbeck | 1.85% |
| 22 | NEU | Neuren Pharmaceuticals | 1.62% |
| 23 | BIOA B | Bioarctic | 1.54% |
| 24 | RAPP | Rapport Therapeutics | 1.35% |
| 25 | TSHA | Taysha Gene Therapies | 1.32% |

All 68 positions with weights: https://tickerinside.com/api/v1/fund/ibrn.json

## Key figures

| Measure | Value |
| --- | --- |
| Last close, 2026-09-04 | 39.06 USD (-0.80% on the day) |
| Expense ratio | 0.47% |
| Positions | 68 |
| Weight in the ten largest | 45.1% |
| Total return, 1 year | 52.3% |
| Total return, 3 years | 75.7% |
| Volatility, annualised | 26.1% |
| Worst fall, 3 years | -31.4% |
| Beta against SPY | 1.13 |

## What does IBRN share with other funds?

| Fund | Overlap by weight | Of IBRN held there | Of that fund in IBRN | Companies in both |
| --- | --- | --- | --- | --- |
| XBI | 14.6% | 56.0% | 14.7% | 22 |
| PBE | 14.5% | 18.7% | 16.3% | 5 |
| IBB | 13.0% | 70.2% | 13.0% | 33 |
| PSCH | 11.8% | 18.4% | 11.8% | 6 |
| IBBQ | 10.8% | 69.5% | 10.8% | 32 |
| BMED | 9.4% | 24.9% | 9.6% | 6 |
| PTH | 9.4% | 17.7% | 9.8% | 5 |
| XPH | 8.5% | 12.9% | 9.7% | 7 |
| RFG | 4.4% | 9.7% | 4.4% | 3 |
| IHE | 3.8% | 11.4% | 3.8% | 5 |
| IWO | 3.8% | 63.4% | 3.9% | 36 |
| QQQJ | 3.8% | 12.4% | 3.8% | 3 |


Method: https://tickerinside.com/how-the-numbers-are-produced/