# Which ETFs hold Vertex Pharmaceuticals (VRTX)?

366 US stock ETFs hold Vertex Pharmaceuticals (VRTX). 122 of them report VRTX in issuer files dated 2026-08-31 to 2026-10-13, and 244 in their latest SEC filing, for periods ended 2026-05-29 to 2026-07-31. Among them, BBH gives VRTX the largest weight, 9.10% (SEC filing for the period ended 2026-06-30). 22 derivative-based funds, three multi-asset funds, one fixed income fund and five funds read from their sponsors' files also hold VRTX outright and are listed apart; TBXU gives it the most weight among them, 7.84% (SEC filing for the period ended 2026-07-31).

Vertex Pharmaceuticals, Biotechnology, $123B market cap. Held by 366 US stock ETFs: 122 in issuer files, 244 in SEC filings. 31 other ETFs holding it outright are listed apart.

Canonical page: https://tickerinside.com/stock/vrtx/
Holdings from each issuer's latest file, dated 2026-08-31 to 2026-10-13, and from each other ETF's latest SEC filing, for periods ended 2026-05-29 to 2026-07-31. Prices through 2026-10-13.
Licence: CC BY 4.0, attribution to TickerInside. Measurements, not investment advice.

No covered fund makes VRTX its largest position; the highest it ranks is #2, in GNMX. The median weight across the 366 holders is 0.28%: 4 of them carry it above 5% and 302 keep it under 1%. Of the 311 covered funds with 500 or more positions, 107 hold VRTX, at weights from under 0.01% to 0.73%.

Over three years VRTX returned 40.1%, with a worst fall of 29.1% and annualised volatility of 30.5%; its beta against SPY over the same weeks is 0.56. Its best calendar year in the data is 2023 at +40.9% and its worst 2024 at -1.0%.

## Is VRTX in VOO, SPY, IVV, QQQ, VTI, SCHD, XLV, VHT or IBB?

VRTX is in 8 of these 9 funds; IBB gives it the most weight, 7.61% (iShares file of 2026-10-12), and SCHD does not hold it.

| ETF | Name | Weight | Rank in the ETF | Holdings dated |
| --- | --- | --- | --- | --- |
| VOO | Vanguard S&P 500 ETF | 0.21% | #84 of 503 | Vanguard file, 2026-08-31 |
| SPY | SPDR S&P 500 ETF Trust | 0.19% | #88 of 504 | SPDR file, 2026-10-12 |
| IVV | iShares Core S&P 500 ETF | 0.19% | #88 of 504 | iShares file, 2026-10-12 |
| QQQ | Invesco QQQ Trust | 0.53% | #40 of 101 | Invesco file, 2026-10-12 |
| VTI | Vanguard Total Stock Market ETF | 0.19% | #84 of 3458 | Vanguard file, 2026-08-31 |
| SCHD | Schwab US Dividend Equity ETF | not held | 99 positions | SEC filing, 2026-05-31 |
| XLV | Health Care Select Sector SPDR Fund | 2.06% | #13 of 62 | SPDR file, 2026-10-12 |
| VHT | Vanguard Health Care ETF | 1.92% | #11 of 411 | Vanguard file, 2026-08-31 |
| IBB | iShares Biotechnology ETF | 7.61% | #3 of 237 | iShares file, 2026-10-12 |

## Which ETFs hold VRTX in their issuer files, and at what weight?

122 funds report VRTX in their own issuer files, dated 2026-08-31 to 2026-10-13; IBBQ gives it the most weight, 7.66%.

| Rank | ETF | Name | Weight | Issuer file |
| --- | --- | --- | --- | --- |
| 1 | IBBQ | Invesco Nasdaq Biotechnology ETF | 7.66% | 2026-10-12 |
| 2 | IBB | iShares Biotechnology ETF | 7.61% | 2026-10-12 |
| 3 | PBE | Invesco Biotechnology & Genome ETF | 4.69% | 2026-10-12 |
| 4 | GNOM | Global X Genomics & Biotechnology ETF | 3.33% | 2026-10-12 |
| 5 | BMED | iShares Health Innovation Active ETF | 3.27% | 2026-10-12 |
| 6 | IDNA | iShares Genomics Immunology and Healthcare ETF | 3.21% | 2026-10-12 |
| 7 | QNXT | iShares Nasdaq-100 ex Top 30 ETF | 2.41% | 2026-10-12 |
| 8 | TECB | iShares U.S. Tech Breakthrough Multisector ETF | 2.40% | 2026-10-12 |
| 9 | XLV | Health Care Select Sector SPDR Fund | 2.06% | 2026-10-12 |
| 10 | IYH | iShares U.S. Healthcare ETF | 2.00% | 2026-10-12 |
| 11 | VHT | Vanguard Health Care ETF | 1.92% | 2026-08-31 |
| 12 | IXJ | iShares Global Healthcare ETF | 1.57% | 2026-10-12 |
| 13 | RSPH | Invesco S&P 500 Equal Weight Health Care ETF | 1.55% | 2026-10-12 |
| 14 | SDG | iShares MSCI Global Sustainable Development Goals ETF | 1.50% | 2026-10-12 |
| 15 | XBI | SPDR S&P Biotech ETF | 1.46% | 2026-10-12 |
| 16 | ESMV | iShares ESG Optimized MSCI USA Min Vol Factor ETF | 1.38% | 2026-10-12 |
| 17 | USMV | iShares MSCI USA Min Vol Factor ETF | 1.34% | 2026-10-12 |
| 18 | QEW | Invesco QQQ Equal Weight ETF | 0.93% | 2026-10-12 |
| 19 | XOEF | iShares S&P 500 ex S&P 100 ETF | 0.74% | 2026-10-12 |
| 20 | QUS | State Street SPDR MSCI USA StrategicFactors℠ ETF | 0.73% | 2026-10-12 |
| 21 | OMFL | Invesco Russell 1000 Dynamic Multifactor ETF | 0.67% | 2026-10-12 |
| 22 | BDVL | iShares Disciplined Volatility Equity Active ETF | 0.65% | 2026-10-12 |
| 23 | MGK | Vanguard Morningstar Mega Cap Growth ETF | 0.64% | 2026-08-31 |
| 24 | XT | iShares Future Exponential Technologies ETF | 0.62% | 2026-10-12 |
| 25 | BDYN | iShares Dynamic Equity Active ETF | 0.55% | 2026-10-12 |
| 26 | QRMI | Global X Nasdaq 100 Risk Managed Income ETF | 0.55% | 2026-10-12 |
| 27 | VUSG | Vanguard Wellington U.S. Growth Active ETF | 0.55% | 2026-10-13 |
| 28 | IQQ | iShares Nasdaq 100 ETF | 0.54% | 2026-10-12 |
| 29 | QYLG | Global X Nasdaq 100 Covered Call & Growth ETF | 0.54% | 2026-10-12 |
| 30 | ACWV | iShares MSCI Global Min Vol Factor ETF | 0.54% | 2026-10-12 |
| 31 | QNDX | State Street SPDR Portfolio Nasdaq 100 ETF | 0.54% | 2026-10-12 |
| 32 | QQQM | Invesco Nasdaq 100 ETF | 0.53% | 2026-10-12 |
| 33 | QQQ | Invesco QQQ Trust | 0.53% | 2026-10-12 |
| 34 | QTR | Global X Nasdaq 100 Tail Risk ETF | 0.53% | 2026-10-12 |
| 35 | QYLD | Global X Nasdaq 100 Covered Call ETF | 0.53% | 2026-10-13 |
| 36 | QCLR | Global X Nasdaq 100 Collar 95-110 ETF | 0.52% | 2026-10-08 |
| 37 | USXF | iShares ESG Advanced MSCI USA ETF | 0.51% | 2026-10-12 |
| 38 | QQMG | Invesco ESG NASDAQ 100 ETF | 0.48% | 2026-10-12 |
| 39 | IWX | iShares Russell Top 200 Value ETF | 0.47% | 2026-10-12 |
| 40 | VOOV | Vanguard S&P 500 Value ETF | 0.46% | 2026-08-31 |
| 41 | SPYV | SPDR Portfolio S&P 500 Value ETF | 0.43% | 2026-10-12 |
| 42 | IVE | iShares S&P 500 Value ETF | 0.43% | 2026-10-12 |
| 43 | QUAL | iShares MSCI USA Quality Factor ETF | 0.43% | 2026-10-12 |
| 44 | SHE | State Street SPDR MSCI USA Gender Diversity ETF | 0.42% | 2026-10-12 |
| 45 | QWLD | State Street SPDR MSCI World StrategicFactors℠ ETF | 0.41% | 2026-10-12 |
| 46 | IUSV | iShares Core S&P U.S. Value ETF | 0.41% | 2026-10-12 |
| 47 | QQA | Invesco QQQ Income Advantage ETF | 0.40% | 2026-10-12 |
| 48 | VUG | Vanguard Growth ETF | 0.39% | 2026-08-31 |
| 49 | SUSA | iShares ESG Optimized MSCI USA ETF | 0.37% | 2026-10-12 |
| 50 | VONV | Vanguard Russell 1000 Value ETF | 0.37% | 2026-08-31 |
| 51 | SUSL | iShares ESG MSCI USA Leaders ETF | 0.36% | 2026-10-12 |
| 52 | AQLT | iShares MSCI Global Quality Factor ETF | 0.36% | 2026-10-12 |
| 53 | DSI | iShares ESG MSCI KLD 400 ETF | 0.35% | 2026-10-12 |
| 54 | IWD | iShares Russell 1000 Value ETF | 0.35% | 2026-10-12 |
| 55 | EGLE | Global X S&P 500 U.S. Revenue Leaders ETF | 0.29% | 2026-10-12 |
| 56 | ILCV | iShares Morningstar Value ETF | 0.26% | 2026-10-12 |
| 57 | MGC | Vanguard Morningstar Mega Cap ETF | 0.25% | 2026-08-31 |
| 58 | ESGU | iShares ESG Aware MSCI USA ETF | 0.24% | 2026-10-12 |
| 59 | PABU | iShares Paris-Aligned Climate Optimized MSCI USA ETF | 0.24% | 2026-10-12 |
| 60 | QVML | Invesco S&P 500 QVM Multi-factor ETF | 0.24% | 2026-10-12 |
| 61 | USCL | iShares Climate Conscious & Transition MSCI USA ETF | 0.23% | 2026-10-12 |
| 62 | TOPC | iShares S&P 500 3% Capped ETF | 0.23% | 2026-10-12 |
| 63 | LCTU | iShares U.S. Carbon Transition Readiness Aware Active ETF | 0.23% | 2026-10-12 |
| 64 | XVV | iShares ESG Select Screened S&P 500 ETF | 0.23% | 2026-10-12 |
| 65 | SPIN | State Street US Equity Premium Income ETF | 0.23% | 2026-10-12 |
| 66 | EGUS | iShares ESG Aware MSCI USA Growth ETF | 0.22% | 2026-10-12 |
| 67 | IWL | iShares Russell Top 200 ETF | 0.22% | 2026-10-12 |
| 68 | KLMN | Invesco MSCI North America Climate ETF | 0.21% | 2026-10-12 |
| 69 | VV | Vanguard Morningstar Large-Cap ETF | 0.21% | 2026-08-31 |
| 70 | ESGV | Vanguard ESG U.S. Stock ETF | 0.21% | 2026-10-13 |
| 71 | SIZE | iShares MSCI USA Size Factor ETF | 0.21% | 2026-10-12 |
| 72 | VOO | Vanguard S&P 500 ETF | 0.21% | 2026-08-31 |
| 73 | XRMI | Global X S&P 500 Risk Managed Income ETF | 0.20% | 2026-10-12 |
| 74 | SPYX | State Street SPDR S&P 500 Fossil Fuel Reserves Free ETF | 0.20% | 2026-10-12 |
| 75 | VONE | Vanguard Russell 1000 ETF | 0.20% | 2026-08-31 |
| 76 | IVVW | iShares S&P 500 BuyWrite ETF | 0.20% | 2026-10-12 |
| 77 | RSP | Invesco S&P 500 Equal Weight ETF | 0.20% | 2026-10-12 |
| 78 | PBUS | Invesco MSCI USA ETF | 0.19% | 2026-10-12 |
| 79 | ILCB | iShares Morningstar U.S. Equity ETF | 0.19% | 2026-10-01 |
| 80 | SPY | SPDR S&P 500 ETF Trust | 0.19% | 2026-10-12 |
| 81 | MLRG | iShares MSCI USA ETF | 0.19% | 2026-10-12 |
| 82 | SPYM | State Street SPDR Portfolio S&P 500 ETF | 0.19% | 2026-10-12 |
| 83 | IVV | iShares Core S&P 500 ETF | 0.19% | 2026-10-12 |
| 84 | GXLC | Global X U.S. 500 ETF | 0.19% | 2026-10-12 |
| 85 | XCLR | Global X S&P 500 Collar 95-110 ETF | 0.19% | 2026-10-08 |
| 86 | XTR | Global X S&P 500 Tail Risk ETF | 0.19% | 2026-10-12 |
| 87 | XYLD | Global X S&P 500 Covered Call ETF | 0.19% | 2026-10-13 |
| 88 | XYLG | Global X S&P 500 Covered Call & Growth ETF | 0.19% | 2026-10-12 |
| 89 | VTI | Vanguard Total Stock Market ETF | 0.19% | 2026-08-31 |
| 90 | VTHR | Vanguard Russell 3000 ETF | 0.19% | 2026-08-31 |
| 91 | EUSA | iShares MSCI USA Equal Weighted ETF | 0.19% | 2026-10-12 |
| 92 | VFMF | Vanguard U.S. Multifactor ETF | 0.18% | 2026-10-13 |
| 93 | ONOF | Global X Adaptive U.S. Risk Management ETF | 0.18% | 2026-10-12 |
| 94 | IWB | iShares Russell 1000 ETF | 0.18% | 2026-10-12 |
| 95 | IYY | iShares Dow Jones U.S. ETF | 0.18% | 2026-10-12 |
| 96 | SPTM | State Street SPDR Portfolio S&P 1500 Composite Stock Market ETF | 0.18% | 2026-10-12 |
| 97 | ENHU | iShares Enhanced Large Cap Core Active ETF | 0.17% | 2026-10-12 |
| 98 | IWV | iShares Russell 3000 ETF | 0.17% | 2026-10-12 |
| 99 | ITOT | iShares Core S&P Total U.S. Stock Market ETF | 0.17% | 2026-10-12 |
| 100 | TOK | iShares MSCI Kokusai ETF | 0.15% | 2026-10-12 |
| 101 | KLMT | Invesco MSCI Global Climate 500 ETF | 0.15% | 2026-10-12 |
| 102 | EVUS | iShares ESG Aware MSCI USA Value ETF | 0.15% | 2026-10-12 |
| 103 | RSPA | Invesco S&P 500 Equal Weight Income Advantage ETF | 0.15% | 2026-10-12 |
| 104 | URTH | iShares MSCI World ETF | 0.14% | 2026-10-12 |
| 105 | IUS | Invesco RAFI Strategic US ETF | 0.14% | 2026-10-12 |
| 106 | PRF | Invesco RAFI US 1000 ETF | 0.14% | 2026-10-12 |
| 107 | INRO | iShares U.S. Industry Rotation Active ETF | 0.14% | 2026-10-12 |
| 108 | VFMO | Vanguard U.S. Momentum Factor ETF | 0.13% | 2026-10-13 |
| 109 | ACWI | iShares MSCI ACWI ETF | 0.12% | 2026-10-12 |
| 110 | MMTM | State Street SPDR S&P 1500 Momentum Tilt ETF | 0.12% | 2026-10-12 |
| 111 | NZAC | State Street SPDR MSCI ACWI Climate Paris Aligned ETF | 0.12% | 2026-10-12 |
| 112 | VT | Vanguard Total World Stock ETF | 0.12% | 2026-08-31 |
| 113 | ILCG | iShares Morningstar Growth ETF | 0.11% | 2026-10-12 |
| 114 | ONEO | State Street SPDR Russell 1000 Momentum Focus ETF | 0.11% | 2026-10-12 |
| 115 | CRBN | iShares Low Carbon Optimized MSCI ACWI ETF | 0.11% | 2026-10-12 |
| 116 | VLU | State Street SPDR S&P 1500 Value Tilt ETF | 0.10% | 2026-10-12 |
| 117 | KOMP | State Street SPDR S&P Kensho New Economies Composite ETF | 0.09% | 2026-10-12 |
| 118 | EQAL | Invesco Russell 1000 Equal Weight ETF | 0.09% | 2026-10-12 |
| 119 | BFLX | iShares Flexible Equity Active ETF | 0.09% | 2026-10-12 |
| 120 | RWL | Invesco S&P 500 Revenue ETF | 0.06% | 2026-10-12 |
| 121 | SPGM | State Street SPDR Portfolio MSCI Global Stock Market ETF | 0.06% | 2026-10-12 |
| 122 | DYNF | iShares U.S. Equity Factor Rotation Active ETF | 0.05% | 2026-10-12 |

The same list as JSON: https://tickerinside.com/api/v1/sec/vrtx.json

## Which ETFs hold VRTX in their latest SEC filing?

244 funds hold VRTX in their latest Form N-PORT filing with the SEC, for periods ended 2026-05-29 to 2026-07-31; BBH gives it the most weight, 9.10%.

| ETF | Name | Weight | Period of the filing | Filing |
| --- | --- | --- | --- | --- |
| BBH | VanEck Biotech ETF | 9.10% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1137360/000141036826086925/ |
| GNMX | Corgi Genomics & Precision Medicine ETF | 6.71% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/2078265/000089418926024712/ |
| LSGR | Natixis Loomis Sayles Focused Growth ETF | 4.78% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1728860/000141036826089915/ |
| FTXH | First Trust Nasdaq Pharmaceuticals ETF | 3.41% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1552740/000094040026032714/ |
| FBT | First Trust NYSE Arca Biotechnology Index Fund | 3.07% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1329377/000094040026033088/ |
| QFRD | Pacer S&P 500 Quality FCF R&D Leaders ETF | 2.98% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1616668/000089418926029036/ |
| HRTS | Tema Heart & Health ETF | 2.93% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1944285/000119312526323015/ |
| PBPH | Portfolio Building Block World Pharma and Biotech Index ETF | 2.82% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/2043390/000200032426004430/ |
| HELX | Franklin Genomic Advancements ETF | 2.75% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1655589/000094040026035124/ |
| KONG | Formidable Fortress ETF | 2.66% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1771146/000100472626007243/ |
| EXEQ | Wedbush ReturnOnLeadership(R) U.S. Large-Cap ETF | 2.49% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/2055464/000094040026038134/ |
| SXQG | ETC 6 Meridian Quality Growth ETF | 2.49% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1452937/000204825126006329/ |
| LRGE | ClearBridge Large Cap Growth Select ETF | 2.28% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1645194/000094040026035182/ |
| CGGG | Capital Group U.S. Large Growth ETF | 2.25% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/2034928/000141036826074212/ |
| TRUH | VanEck Healthcare TruSector ETF | 2.21% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1137360/000141036826086932/ |
| QQEW | First Trust Nasdaq-100 Select Equal Weight ETF | 2.18% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1329377/000094040026033037/ |
| GPT | Intelligent Alpha Atlas ETF | 2.09% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004125/ |
| QQXT | First Trust NASDAQ-100 Ex-Technology Sector Index Fund | 2.07% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1329377/000094040026033033/ |
| RND | First Trust Bloomberg R&D Leaders ETF | 2.06% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1552740/000094040026032763/ |
| ASLV | Allspring Special Large Value ETF | 2.05% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1611331/000141036826097436/ |
| NBFR | Innovator Nasdaq-100 Managed 10 Buffer ETF | 1.97% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1415726/000089418926028242/ |
| DRUP | GraniteShares Nasdaq Select Disruptors ETF | 1.94% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1689873/000104916926002480/ |
| HTEC | ROBO Global Healthcare Technology and Innovation ETF | 1.91% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1452937/000204825126008259/ |
| FFLS | The Future Fund Long/Short ETF | 1.84% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1518042/000091047226010792/ |
| FHLC | Fidelity MSCI Health Care Index ETF | 1.76% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/945908/000141036826097243/ |
| QQQG | Pacer Nasdaq 100 Top 50 Cash Cows Growth Leaders ETF | 1.64% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1616668/000089418926029016/ |
| REGS | Columbia Large Cap Growth ETF | 1.58% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1551950/000141036826088938/ |
| CGUS | Capital Group Core Equity ETF | 1.58% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1870102/000141036826074216/ |
| CGGR | Capital Group Growth ETF | 1.56% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1869991/000141036826074219/ |
| NULG | Nuveen ESG Large-Cap Growth ETF | 1.50% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1635073/000163507326000483/ |
| TOLL | Tema Durable Quality ETF | 1.49% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1944285/000119312526323018/ |
| GDOC | Goldman Sachs Future Health Care Equity ETF | 1.48% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028080/ |
| BBP | Virtus Biotech Etf | 1.48% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1559109/000094040026039012/ |
| JEPI | JPMorgan Equity Premium Income ETF | 1.46% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126021114/ |
| PINK | Simplify Health Care ETF | 1.45% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1810747/000094040026033603/ |
| FFND | One Global ETF | 1.45% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1518042/000091047226010788/ |
| SEIQ | SEI Enhanced U.S. Large Cap Quality Factor ETF | 1.36% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1888997/000204825126007482/ |
| WDNA | WisdomTree BioRevolution Fund | 1.34% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1350487/000094040026036216/ |
| CGVV | Capital Group U.S. Large Value ETF | 1.28% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/2034928/000141036826074222/ |
| RILA | Indexperts Gorilla Aggressive Growth ETF | 1.26% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1484018/000200032426005528/ |
| MEDI | Harbor Health Care ETF | 1.22% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1860434/000141036826099302/ |
| CGBL | Capital Group Core Balanced ETF | 1.20% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1970533/000141036826086158/ |
| CGGO | Capital Group Global Growth Equity ETF | 1.14% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1870116/000141036826074218/ |
| AGRW | Allspring LT Large Growth ETF | 1.11% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1611331/000141036826097424/ |
| QQQE | Direxion NASDAQ-100 Equal Weighted Index Shares | 1.09% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1424958/000119312526404437/ |
| SQS | Sapient Quality Select ETF | 1.07% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004406/ |
| LST | Leuthold Select Industries ETF | 1.03% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1511699/000119312526368799/ |
| RFFC | ALPS Active Equity Opportunity ETF | 0.97% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1414040/000104916926001876/ |
| LGRO | Level Four Large Cap Growth Active ETF | 0.96% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1414040/000104916926001878/ |
| ENDW | Cambria Endowment Style ETF | 0.90% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026003670/ |
| HEMI | Hartford Equity Premium Income ETF | 0.90% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1501825/000141036826101362/ |
| PJFG | PGIM Jennison Focused Growth ETF | 0.86% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1727074/000094040026028359/ |
| JDOC | JPMorgan Healthcare Leaders ETF | 0.81% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126023544/ |
| FXH | First Trust Health Care AlphaDEX Fund | 0.81% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1383496/000094040026037829/ |
| COWG | Pacer US Large Cap Cash Cows Growth Leaders ETF | 0.81% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1616668/000089418926028995/ |
| CGDV | Capital Group Dividend Value ETF | 0.80% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1870128/000141036826074213/ |
| LVDS | JPMorgan Fundamental Data Science Large Value ETF | 0.80% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126021095/ |
| XIGV | Defiance US 100 Tech Ex Software ETF | 0.79% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1540305/000119312526373333/ |
| JOET | Virtus Terranova U.S. Quality Momentum ETF | 0.77% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1648403/000094040026038966/ |
| MODL | VictoryShares WestEnd US Sector ETF | 0.76% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1547580/000100472626007539/ |
| LRND | NYLIM U.S. Large Cap R&D Leaders ETF | 0.69% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1415995/000094040026038570/ |
| SGLC | SGI U.S. Large Cap Core ETF | 0.68% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/831114/000119312526320153/ |
| LRGC | AB US Large Cap Strategic Equities ETF | 0.68% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1496608/000141036826074951/ |
| AVIE | Avantis Inflation Focused Equity ETF | 0.68% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1710607/000119312526323995/ |
| TNXT | T. Rowe Price Innovation Leaders ETF | 0.67% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1795351/000109926326009634/ |
| QIDX | Indexperts Quality Earnings Focused ETF | 0.65% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1484018/000200032426005531/ |
| GPIQ | Goldman Sachs Nasdaq-100 Premium Income ETF | 0.63% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026034789/ |
| QGRW | WisdomTree U.S. Quality Growth Fund | 0.63% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1350487/000094040026036267/ |
| TUG | STF Tactical Growth ETF | 0.62% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1683471/000119312526367648/ |
| JEPQ | JPMorgan Nasdaq Equity Premium Income ETF | 0.59% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126021122/ |
| SEPQ | STF Tactical Growth & Income ETF | 0.58% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1683471/000119312526367641/ |
| CAPE | DoubleLine Shiller Cape U.S. Equities ETF | 0.58% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1886172/000207169126018692/ |
| PTNQ | Pacer Trendpilot 100 ETF | 0.55% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1616668/000089418926029003/ |
| QQQI | NEOS Nasdaq-100(R) High Income ETF | 0.55% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1848758/000089418926023149/ |
| QQQH | NEOS Nasdaq-100(R) Hedged Equity Income ETF | 0.55% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1848758/000089418926023151/ |
| QQWZ | Pacer Cash COWZ 100-Nasdaq 100 Rotator ETF | 0.54% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1616668/000089418926029014/ |
| COPY | Tweedy, Browne Insider + Value ETF | 0.53% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1618627/000119312526319508/ |
| CRTC | Xtrackers US National Critical Technologies ETF | 0.53% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1503123/000094040026028796/ |
| CDEI | Calvert US Large-Cap Diversity, Equity and Inclusion Index ETF | 0.53% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1676326/000207169126018740/ |
| DFUV | Dimensional U.S. Marketwide Value ETF | 0.52% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009219/ |
| AFGR | First Trust Multi-Manager Large Growth ETF | 0.51% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1667919/000094040026027839/ |
| QSIX | Pacer Metaurus Nasdaq 100 Dividend Multiplier 600 ETF | 0.51% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1616668/000089418926029048/ |
| WOMN | Impact Shares Women's Empowerment ETF | 0.50% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1722388/000200032426003834/ |
| ACLC | American Century Large Cap Equity ETF | 0.50% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1710607/000119312526323969/ |
| BAMG | Brookstone Growth Stock ETF | 0.49% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1644419/000091047226010773/ |
| RCGE | RockCreek Global Equality ETF | 0.48% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004397/ |
| GINN | Goldman Sachs Innovate Equity ETF | 0.47% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028085/ |
| ACGR | American Century Large Cap Growth ETF | 0.47% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1710607/000119312526323972/ |
| XQQI | NEOS Boosted Nasdaq-100(R) High Income ETF | 0.45% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1848758/000089418926023147/ |
| BTAL | AGF U.S. Market Neutral Anti-Beta Fund | 0.44% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1479599/000207169126018347/ |
| XCHG | AB US Equity ETF | 0.44% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1496608/000141036826074962/ |
| GGUS | Goldman Sachs MarketBeta(R) Russell 1000 Growth Equity ETF | 0.44% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028141/ |
| ESG | FlexShares STOXX US ESG Select Index Fund | 0.43% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1491978/000207169126023460/ |
| TMFC | Motley Fool 100 Index ETF | 0.43% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/831114/000119312526320125/ |
| CGGE | Capital Group Global Equity ETF | 0.43% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/2008374/000141036826074215/ |
| TEC | Harbor Transformative Technologies ETF | 0.42% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1860434/000141036826099299/ |
| MNZL | Manzil Russell Halal USA Broad Market ETF | 0.42% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004388/ |
| QQH | HCM Defender 100 Index ETF | 0.40% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1537140/000091047226013060/ |
| RGLO | Russell Investments Global Equity ETF | 0.40% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/2042513/000141036826084769/ |
| SCHG | Schwab U.S. Large-Cap Growth ETF | 0.40% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1454889/000141036826075030/ |
| SFY | Sofi Select 500 ETF | 0.39% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1742912/000200032426003230/ |
| VPX | Variant Perception Cycle Aware US Equity ETF | 0.39% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026003724/ |
| JUSA | JPMorgan U.S. Research Enhanced Large Cap ETF | 0.39% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126021129/ |
| LCDS | JPMorgan Fundamental Data Science Large Core ETF | 0.38% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126021069/ |
| ROCY | JPMorgan Equity Premium Yield ETF | 0.38% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126021128/ |
| FTC | First Trust Large Cap Growth AlphaDEX Fund | 0.37% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1383496/000094040026037842/ |
| WINN | Harbor Long-Term Growers ETF | 0.37% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1860434/000141036826099285/ |
| FWD | AB Disruptors ETF | 0.37% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1496608/000141036826074974/ |
| AVSU | Avantis Responsible U.S. Equity ETF | 0.37% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1710607/000119312526324011/ |
| NULC | Nuveen ESG Large-Cap ETF | 0.37% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1635073/000163507326000473/ |
| JOYT | JPMorgan Equity and Options Total Return ETF | 0.36% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126023528/ |
| PRXG | Praxis Impact Large Cap Growth ETF | 0.35% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/912900/000089418926022752/ |
| IQSU | NYLIM Candriam U.S. Large Cap Equity ETF | 0.35% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1415995/000094040026038560/ |
| HELO | JPMorgan Hedged Equity Laddered Overlay ETF | 0.35% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126023551/ |
| USSG | Xtrackers MSCI USA Selection Equity ETF | 0.33% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1503123/000094040026028746/ |
| REVS | Columbia Research Enhanced Value ETF | 0.33% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1551950/000141036826100658/ |
| HLAL | Wahed FTSE USA Shariah ETF | 0.32% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1683471/000119312526325595/ |
| AVUQ | Avantis U.S. Quality ETF | 0.32% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1710607/000119312526324020/ |
| ESGG | FlexShares STOXX Global ESG Select Index Fund | 0.32% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1491978/000207169126023448/ |
| SSPY | Stratified LargeCap Index ETF | 0.31% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1547950/000091047226013046/ |
| WRND | NYLIM Global Equity R&D Leaders ETF | 0.30% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1415995/000094040026038569/ |
| SPUS | Sp Funds S&P 500 Sharia Industry Exclusions ETF | 0.30% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1742912/000200032426003242/ |
| DFLV | Dimensional US Large Cap Value ETF | 0.30% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009201/ |
| MPLY | Monopoly ETF | 0.29% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1506213/000100472626009406/ |
| QLV | FlexShares US Quality Low Volatility Index Fund | 0.29% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1491978/000207169126023455/ |
| STOX | Horizon Core Equity ETF | 0.29% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1643174/000119312526300739/ |
| SFTY | Horizon Managed Risk ETF | 0.29% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1643174/000119312526300747/ |
| SPXT | ProShares S&P 500 Ex-Technology ETF | 0.28% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017394/ |
| JAVA | JPMorgan Active Value ETF | 0.28% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126021105/ |
| NBCR | Neuberger Core Equity ETF | 0.28% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1506001/000141036826075463/ |
| TGRT | T. Rowe Price Growth ETF | 0.26% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1795351/000109926326009626/ |
| XMAG | Defiance Large Cap ex-Mag 7 ETF | 0.26% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1924868/000200032426003032/ |
| ACVF | American Conservative Values ETF | 0.25% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1771146/000100472626009289/ |
| HQGO | Hartford US Quality Growth ETF | 0.25% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1605803/000141036826101353/ |
| STXG | Strive 1000 Growth ETF | 0.25% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004162/ |
| LOPP | Gabelli Love Our Planet & People ETF | 0.25% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1748425/000094040026036158/ |
| ONEQ | Fidelity Nasdaq Composite Index ETF | 0.25% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/205323/000003540226004684/ |
| USNZ | Xtrackers Net Zero Pathway Paris Aligned US Equity ETF | 0.24% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1503123/000094040026028744/ |
| DFVE | DoubleLine Fortune 500 Equal Weight ETF | 0.24% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1886172/000207169126018688/ |
| TVAL | T. Rowe Price Value ETF | 0.24% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1795351/000109926326009625/ |
| PQUS | Pictet AI Enhanced US Equity ETF | 0.24% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1969674/000100371526003146/ |
| AAEQ | Alpha Architect US Equity 2 ETF | 0.23% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004070/ |
| CVLC | Calvert US Large-Cap Core Responsible Index ETF | 0.23% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1676326/000207169126018748/ |
| TSPA | T. Rowe Price U.S. Equity Research ETF | 0.23% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1795351/000109926326009618/ |
| MSLC | Morgan Stanley Pathway Large Cap Equity ETF | 0.22% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/875186/000100371526002821/ |
| JSTC | Adasina Social Justice All Cap Global ETF | 0.22% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1742912/000200032426003224/ |
| BFOR | Barrons 400 ETF | 0.22% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1414040/000104916926001865/ |
| AAUA | Alpha Architect US Equity 3 ETF | 0.22% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004071/ |
| AAUS | Alpha Architect US Equity ETF | 0.22% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004072/ |
| GUSE | Goldman Sachs Enhanced U.S. Equity ETF | 0.22% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028070/ |
| USCA | Xtrackers MSCI USA Climate Action Equity ETF | 0.21% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1503123/000094040026028747/ |
| PWS | Pacer WealthShield ETF | 0.21% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1616668/000089418926029039/ |
| FINA | Fidelity MSCI North American Subset Index ETF | 0.21% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/945908/000003540226006207/ |
| GPIX | Goldman Sachs S&P 500 Premium Income ETF | 0.21% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026034787/ |
| DSPY | Tema S&P 500 Historical Weight ETF Strategy | 0.21% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1944285/000119312526323020/ |
| GSEW | Goldman Sachs Equal Weight U.S. Large Cap Equity ETF | 0.21% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028073/ |
| EEE | Cyber Hornet S&P 500 & Ethereum 75/25 Strategy ETF | 0.20% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1345125/000089418926024016/ |
| XXX | Cyber Hornet S&P 500 & XRP 75/25 Strategy ETF | 0.20% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1345125/000089418926024018/ |
| SPXN | ProShares S&P 500 Ex-Financials ETF | 0.20% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017408/ |
| RAUS | Racwi US ETF | 0.20% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004148/ |
| STXF | Strive 500 ETF | 0.20% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004161/ |
| USPX | Franklin U.S. Equity Index ETF | 0.20% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1655589/000094040026035112/ |
| SPYI | NEOS S&P 500(R) High Income ETF | 0.20% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1848758/000089418926023148/ |
| VSLU | Applied Finance Valuation Large Cap ETF | 0.19% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1771146/000100472626007194/ |
| PBP | Invesco S&P 500 BuyWrite ETF | 0.19% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1209466/000120946626001440/ |
| OALC | Oneascent Large Cap Core ETF | 0.19% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1199046/000091047226011109/ |
| BKLC | BNY Mellon US Large Cap Core Equity ETF | 0.19% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1493580/000094040026038310/ |
| PTLC | Pacer Trendpilot US Large Cap ETF | 0.19% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1616668/000089418926029043/ |
| JUST | Goldman Sachs JUST U.S. Large Cap Equity ETF | 0.19% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028074/ |
| BBUS | JPMorgan Betabuilders U.S. Equity ETF | 0.19% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126023533/ |
| FLCG | Federated Hermes MDT Large Cap Growth ETF | 0.19% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1849998/000184999826000163/ |
| ACIO | Aptus Collared Investment Opportunity ETF | 0.19% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1540305/000119312526407774/ |
| VOTE | TCW Transform 500 ETF | 0.19% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1831313/000100371526003512/ |
| FAD | First Trust Multi Cap Growth AlphaDEX Fund | 0.19% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1383496/000094040026037835/ |
| SPYH | NEOS S&P 500(R) Hedged Equity Income ETF | 0.18% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1848758/000089418926023145/ |
| SPXE | ProShares S&P 500 Ex-Energy ETF | 0.18% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017446/ |
| ADME | Aptus Drawdown Managed Equity ETF | 0.18% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1540305/000119312526407775/ |
| TOV | JLens 500 Jewish Advocacy U.S. ETF | 0.18% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026004416/ |
| USEW | Cambria US EW ETF | 0.18% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026003723/ |
| GSUS | Goldman Sachs MarketBeta U.S. Equity ETF | 0.18% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028137/ |
| RWLC | Rayliant NxtGen Multifactor US Equity ETF | 0.18% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1593547/000204825126007153/ |
| WAMA | WisdomTree U.S. Adaptive Moving Average Fund | 0.18% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1350487/000094040026036305/ |
| DFUS | Dimensional U.S. Equity Market ETF | 0.18% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009215/ |
| RECS | Columbia Research Enhanced Core ETF | 0.18% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1551950/000141036826100635/ |
| DFSU | Dimensional US Sustainability Core 1 ETF | 0.17% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009183/ |
| VOXP | Vox Populi ETF | 0.17% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1027596/000119312526406592/ |
| WCEO | Hypatia Women CEO ETF | 0.17% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1552947/000091047226015127/ |
| QDPL | Pacer Metaurus US Large Cap Dividend Multiplier 400 ETF | 0.17% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1616668/000089418926029047/ |
| ROUS | Hartford Multifactor US Equity ETF | 0.17% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1605803/000141036826101393/ |
| XSPI | NEOS Boosted S&P 500(R) High Income ETF | 0.17% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1848758/000089418926023153/ |
| BKLG | BNY Mellon US Large Cap Equity Growth ETF | 0.17% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1493580/000094040026038303/ |
| OPTZ | Optimize Strategy Index ETF | 0.17% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1970751/000119312526376494/ |
| JQUA | JPMorgan U.S. Quality Factor ETF | 0.17% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126023568/ |
| SCHX | Schwab U.S. Large-Cap ETF | 0.17% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1454889/000141036826075026/ |
| NTSX | WisdomTree U.S. Efficient Core Fund | 0.17% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1350487/000094040026036309/ |
| GUSA | Goldman Sachs MarketBeta U.S. 1000 Equity ETF | 0.16% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1882879/000094040026028124/ |
| SCHK | Schwab 1000 Index ETF | 0.16% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1454889/000141036826075028/ |
| TILT | FlexShares Morningstar US Market Factor Tilt Index Fund | 0.16% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1491978/000207169126023441/ |
| CFA | VictoryShares US 500 Volatility Wtd ETF | 0.16% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1547580/000100472626007510/ |
| SCHB | Schwab U.S. Broad Market ETF | 0.16% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1454889/000141036826075044/ |
| CFO | VictoryShares US 500 Enhanced Volatility Wtd ETF | 0.16% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1547580/000100472626007530/ |
| LGH | HCM Defender 500 Index ETF | 0.15% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1537140/000091047226013067/ |
| GQI | Natixis Gateway Quality Income ETF | 0.15% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1526787/000141036826089925/ |
| BBB | Cyber Hornet S&P 500 and Bitcoin 75/25 Strategy ETF | 0.15% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1345125/000089418926024017/ |
| PHDG | Invesco S&P 500 Downside Hedged ETF | 0.15% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1418144/000141814426000465/ |
| HCMT | Direxion HCM Tactical Enhanced US ETF | 0.15% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1424958/000119312526404430/ |
| EPS | WisdomTree U.S. LargeCap Fund | 0.15% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1350487/000094040026036286/ |
| AIEQ | Amplify AI Powered Equity ETF | 0.15% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1633061/000119312526372652/ |
| APUE | ActivePassive U.S. Equity ETF | 0.14% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1141819/000119312526320601/ |
| FLCC | Federated Hermes MDT Large Cap Core ETF | 0.14% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1849998/000184999826000162/ |
| AVUS | Avantis U.S. Equity ETF | 0.14% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1710607/000119312526324013/ |
| DFVX | Dimensional US Large Cap Vector ETF | 0.14% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009185/ |
| AVLC | Avantis U.S. Large Cap Equity ETF | 0.14% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1710607/000119312526324099/ |
| GDE | WisdomTree Efficient Gold Plus Equity Strategy Fund | 0.14% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1350487/000094040026028870/ |
| TACU | T. Rowe Price Active Core U.S. Equity ETF | 0.14% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1795351/000109926326009633/ |
| DFAU | Dimensional US Core Equity Market ETF | 0.13% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009204/ |
| KOKU | Xtrackers MSCI Kokusai Equity ETF | 0.13% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1503123/000094040026028751/ |
| JHML | John Hancock Multifactor Large Cap ETF | 0.13% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1478482/000147848226000287/ |
| NANC | Unusual Whales Subversive Democratic Trading ETF | 0.12% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1742912/000200032426003777/ |
| GSWO | Goldman Sachs ActiveBeta World Equity ETF | 0.11% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028072/ |
| LGDX | Intech S&P Large Cap Diversified Alpha ETF | 0.11% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1722388/000200032426005383/ |
| MFUS | PIMCO RAFI Dynamic Multi-Factor U.S. Equity ETF | 0.10% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1479360/000141036826090097/ |
| RAA | SMI 3Fourteen REAL Asset Allocation ETF | 0.10% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1771146/000119312526368459/ |
| DFAL | Dimensional US Large Cap Core Equity Market ETF | 0.10% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009187/ |
| DCOR | Dimensional US Core Equity 1 ETF | 0.10% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009192/ |
| SPUT | Innovator Equity Premium Income - Daily PutWrite ETF | 0.10% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1415726/000089418926028281/ |
| EQL | ALPS Equal Sector Weight ETF | 0.09% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1414040/000104916926001875/ |
| DFAC | Dimensional U.S. Core Equity 2 ETF | 0.09% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009214/ |
| FNDX | Schwab Fundamental U.S. Large Company ETF | 0.09% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1454889/000141036826075024/ |
| FEX | First Trust Large Cap Core AlphaDEX Fund | 0.09% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1383496/000094040026037836/ |
| FNDB | Schwab Fundamental U.S. Broad Market ETF | 0.08% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1454889/000141036826075039/ |
| GSLC | Goldman Sachs ActiveBeta(R) U.S. Large Cap Equity ETF | 0.08% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028061/ |
| GEW | Cambria Global EW ETF | 0.07% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1592900/000159290026003676/ |
| GTPE | Goldman Sachs MSCI World Private Equity Return Tracker ETF | 0.07% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1479026/000094040026028139/ |
| QARP | Xtrackers Russell 1000 US Quality at a Reasonable Price ETF | 0.07% | 2026-05-29 | https://www.sec.gov/Archives/edgar/data/1503123/000094040026028754/ |
| PRXV | Praxis Impact Large Cap Value ETF | 0.06% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/912900/000089418926022753/ |
| GSPY | Gotham Enhanced 500 ETF | 0.06% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1742912/000200032426003771/ |
| MHIP | Milliman Healthcare Inflation Plus ETF | 0.05% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/2096904/000089418926023702/ |
| DXUV | Dimensional US Vector Equity ETF | 0.04% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1816125/000100472626009182/ |
| AVTM | Avantis Total Equity Markets ETF | 0.03% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1710607/000119312526324016/ |
| SPXD | Xtrackers S&P 500 Diversified Sector Weight ETF | 0.01% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1503123/000094040026028809/ |
| THEQ | T. Rowe Price Hedged Equity ETF | 0.01% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1795351/000109926326009629/ |
| EBI | Longview Advantage ETF | under 0.01% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1618627/000119312526319465/ |
| NPFE | NPF Core Equity ETF | under 0.01% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1936157/000193615726000486/ |

## How many ETFs held VRTX each year since 2019?

348 of today's US stock ETFs held VRTX in their SEC reports for the second quarter of 2026, against 117 for the fourth quarter of 2019.

| Quarter | ETFs holding it | Largest weight |
| --- | --- | --- |
| Q4 2019 | 117 | IBB 6.69% |
| Q4 2020 | 168 | BBH 5.22% |
| Q4 2021 | 197 | BBH 5.35% |
| Q4 2022 | 236 | IBBQ 7.32% |
| Q4 2023 | 283 | BBH 10.68% |
| Q4 2024 | 277 | BBH 10.42% |
| Q4 2025 | 305 | BBH 9.12% |
| Q2 2026 | 348 | BBH 9.10% |

VRTX in the SEC reports (Form N-PORT) of today's US stock ETFs, Q4 2019 to Q2 2026, every quarter in https://tickerinside.com/api/v1/sec/vrtx.json (etf_holders_since_2019). How these are counted: https://tickerinside.com/how-the-numbers-are-produced/#sec-history

## Which ETFs have swap, futures or option exposure to VRTX?

Two funds reference VRTX through swaps, futures or options in their latest SEC filing: IINC (written puts 0.90%) and IALT (direction not stated). These figures are notional exposure, in percent of each fund's net assets, not shares held, and none of these funds is counted among the 366 holders of VRTX above.

| ETF | Name | Notional exposure, not shares held | Instruments | Period of the filing |
| --- | --- | --- | --- | --- |
| IINC | Alki Consolidated Income ETF | Written puts 0.90% | option | 2026-06-30 |
| IALT | iShares Systematic Alternatives Active ETF | Direction not stated | swap | 2026-07-31 |

## Which other ETFs hold VRTX outright?

22 derivative-based funds, three multi-asset funds, one fixed income fund and five funds read from their sponsors' files hold VRTX outright in SEC filings and sponsors' files dated 2026-05-31 to 2026-10-13; TBXU gives it the most weight, 7.84%. None of them is counted among the 366 US stock ETFs above.

| ETF | Name | Kind of ETF | Held outright | Holdings dated | Source |
| --- | --- | --- | --- | --- | --- |
| TBXU | Direxion Daily Biotech Top 5 Bull 2X ETF | Derivative-based | 7.84% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1424958/000119312526404484/ |
| BIB | ProShares Ultra Nasdaq Biotechnology | Derivative-based | 4.65% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017441/ |
| HLTH | Tema Healthcare AI ETF | Sponsor's file | 4.12% | 2026-10-13 | https://temaetfs.com/hubfs/Website/Holdings/HLTH-holdings-10132026.csv |
| RXL | ProShares Ultra Health Care | Derivative-based | 1.64% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017377/ |
| CURE | Direxion Daily Healthcare Bull 3X Shares | Derivative-based | 1.39% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1424958/000119312526404480/ |
| KWIN | KraneShares Wahed Alternative Income Index ETF | Multi-asset | 1.06% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1547576/000204825126007242/ |
| BAGX | EA Bridgeway Aggressive Investors ETF | Sponsor's file | 0.79% | 2026-09-30 | https://bridgewayetfs.com/bagx/ |
| LABU | Direxion Daily S&P Biotech Bull 3X Shares | Derivative-based | 0.75% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1424958/000119312526404436/ |
| NDOW | Anydrus Advantage ETF | Multi-asset | 0.74% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1719812/000100472626007573/ |
| FLSP | Franklin Systematic Style Premia ETF | Derivative-based | 0.62% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1655589/000094040026035127/ |
| KIQQ | KraneShares InspereX Nasdaq Dynamic Buffered High Income Index ETF | Derivative-based | 0.61% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1547576/000204825126007251/ |
| QB | ProShares Nasdaq-100 Dynamic Buffer ETF | Derivative-based | 0.52% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017334/ |
| IQQQ | ProShares Nasdaq-100 High Income ETF | Derivative-based | 0.42% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017338/ |
| CSM | ProShares Large Cap Core Plus | Derivative-based | 0.33% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017365/ |
| QLD | ProShares Ultra QQQ | Derivative-based | 0.31% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017375/ |
| EQQQ | ProShares Ultra QQQ Equal Weight | Sponsor's file | 0.18% | 2026-10-13 | https://accounts.profunds.com/etfdata/ByFund/EQQQ-psdlyhld.csv |
| AAUB | Alpha Architect US Equity 4 ETF | Sponsor's file | 0.18% | 2026-09-30 | https://funds.alphaarchitect.com/aaub/ |
| SPUU | Direxion Daily S&P 500 Bull 2X Shares | Derivative-based | 0.17% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1424958/000119312526404474/ |
| NTSD | WisdomTree Efficient U.S. Plus International Equity Fund | Derivative-based | 0.17% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1350487/000094040026036218/ |
| TQQQ | ProShares UltraPro QQQ | Derivative-based | 0.15% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017348/ |
| FB | ProShares S&P 500 Dynamic Buffer ETF | Derivative-based | 0.15% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017413/ |
| ISPY | ProShares S&P 500 High Income ETF | Derivative-based | 0.15% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017364/ |
| SPXL | Direxion Daily S&P 500 Bull 3X Shares | Derivative-based | 0.14% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1424958/000119312526404527/ |
| SSO | ProShares Ultra S&P500 | Derivative-based | 0.11% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017379/ |
| SSS | Cyber Hornet S&P 500 & Solana 75/25 Strategy ETF | Multi-asset | 0.10% | 2026-06-30 | https://www.sec.gov/Archives/edgar/data/1345125/000089418926024015/ |
| JPFP | JPMorgan Managed Futures Plus ETF | Derivative-based | 0.08% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1485894/000207169126023567/ |
| UPRO | ProShares UltraPro S&P500 | Derivative-based | 0.08% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017443/ |
| HRSK | Toews Agility Shares Hedged Risk ETF | Derivative-based | 0.07% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1314414/000091047226015198/ |
| URSP | ProShares Ultra S&P 500 Equal Weight | Derivative-based | 0.07% | 2026-05-31 | https://www.sec.gov/Archives/edgar/data/1174610/000207169126017345/ |
| CGFS | CG Flagship Equity ETF | Sponsor's file | 0.05% | 2026-09-30 | https://cgflagshipetfs.com/ |
| CSHP | iShares Dynamic Short-Term Active ETF | Fixed income | 0.04% | 2026-07-31 | https://www.sec.gov/Archives/edgar/data/1761055/000141036826099885/ |

## Key figures

| Measure | Value |
| --- | --- |
| Last close, 2026-10-12 | 507.0 USD (-0.60% on the day) |
| Total return, 1 year | 21.6% |
| Total return, 3 years | 40.1% |
| Total return, 5 years | 176.3% |
| Volatility, annualised | 30.5% |
| Worst fall, 3 years | -29.1% |
| Beta against SPY | 0.56 |
| Market cap | $122.9B |
| Price to earnings, trailing | 28.3 |
| Dividend yield | 0.00% |
| US stock ETFs holding it | 366 |
| Broad ETFs holding it, 500 positions or more | 107 of 311 |
| $100 three years ago became | $140 |

## How has VRTX done, year by year?

| Year | Total return |
| --- | --- |
| 2026 | 11.8% |
| 2025 | 12.6% |
| 2024 | -1.0% |
| 2023 | 40.9% |
| 2022 | 31.5% |

## What would diversify VRTX?

The stocks that have moved least like VRTX, among those held by ten or more covered ETFs, closed-end funds left out. A measurement of co-movement, not a suggestion.

| Ticker | Name | Correlation, 104 weeks | Reads as |
| --- | --- | --- | --- |
| TPC | Tutor Perini Corporation | -0.29 | moves the opposite way |
| INFU | InfuSystems Holdings, Inc. | -0.23 | moves the opposite way |
| STAA | STAAR Surgical Company | -0.21 | moves the opposite way |
| BCO | Brinks Company | -0.19 | moves the opposite way |
| DHC | Diversified Healthcare Trust | -0.16 | moves the opposite way |
| AMRC | Ameresco, Inc. | -0.15 | moves the opposite way |

## What moves with VRTX?

| Ticker | Name | Correlation, 104 weeks | Reads as |
| --- | --- | --- | --- |
| LLY | Lilly (Eli) | 0.56 | loosely linked |
| AMGN | Amgen | 0.49 | loosely linked |
| BIIB | Biogen | 0.43 | loosely linked |
| AURA | Aura Biosciences, Inc. | 0.42 | loosely linked |
| MRK | Merck & Co. | 0.42 | loosely linked |
| KURA | Kura Oncology, Inc. | 0.42 | loosely linked |

## Which ETF has the largest weight in VRTX?

BBH, at 9.10% in its SEC filing for the period ended 2026-06-30, where VRTX is position #3 of 24, followed by IBBQ at 7.66% and IBB at 7.61%.

| ETF | Name | Weight | Rank in the ETF | Positions | Holdings dated |
| --- | --- | --- | --- | --- | --- |
| BBH | VanEck Biotech ETF | 9.10% | #3 | 24 | SEC filing, 2026-06-30 |
| IBBQ | Invesco Nasdaq Biotechnology ETF | 7.66% | #3 | 246 | issuer file, 2026-10-12 |
| IBB | iShares Biotechnology ETF | 7.61% | #3 | 237 | issuer file, 2026-10-12 |
| GNMX | Corgi Genomics & Precision Medicine ETF | 6.71% | #2 | 58 | SEC filing, 2026-06-30 |
| LSGR | Natixis Loomis Sayles Focused Growth ETF | 4.78% | #6 | 21 | SEC filing, 2026-06-30 |
| PBE | Invesco Biotechnology & Genome ETF | 4.69% | #7 | 30 | issuer file, 2026-10-12 |
| FTXH | First Trust Nasdaq Pharmaceuticals ETF | 3.41% | #9 | 50 | SEC filing, 2026-06-30 |
| GNOM | Global X Genomics & Biotechnology ETF | 3.33% | #9 | 50 | issuer file, 2026-10-12 |
| BMED | iShares Health Innovation Active ETF | 3.27% | #11 | 54 | issuer file, 2026-10-12 |
| IDNA | iShares Genomics Immunology and Healthcare ETF | 3.21% | #12 | 47 | issuer file, 2026-10-12 |

## Cite this page

TickerInside, Vertex Pharmaceuticals (VRTX), holders from each covered fund's own file and from SEC Form N-PORT filings, each dated, prices through 2026-10-13, https://tickerinside.com/stock/vrtx/, CC BY 4.0

    <a href="https://tickerinside.com/stock/vrtx/">TickerInside</a> (https://tickerinside.com/stock/vrtx/)

Method: https://tickerinside.com/how-the-numbers-are-produced/