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XPH holdings and overlap
What does XPH hold, as of its issuer file of 2026-09-03?
XPH holds 63 positions as of the issuer file dated 2026-09-03. The three largest are Amylyx Pharmaceuticals Inc at 3.8%, MBX Biosciences Inc at 2.98% and Ataibeckley Inc at 2.92%.
| Rank | Company | Weight | Weight bar |
|---|---|---|---|
| 1 | AMLX Amylyx Pharmaceuticals Inc | 3.8% | |
| 2 | MBX MBX Biosciences Inc | 2.98% | |
| 3 | ATAI Ataibeckley Inc | 2.92% | |
| 4 | OMER Omeros Corp | 2.82% | |
| 5 | DFTX Definium Therapeutics Inc | 2.46% | |
| 6 | ELVN Enliven Therapeutics Inc | 2.43% | |
| 7 | NUVB Nuvation Bio Inc | 2.22% | |
| 8 | CORT Corcept Therapeutics Inc | 2.17% | |
| 9 | ETON Eton Pharmaceuticals Inc | 2.13% | |
| 10 | TARS Tarsus Pharmaceuticals Inc | 2.04% | |
| 11 | NKTR Nektar Therapeutics | 2.02% | |
| 12 | MRK Merck + Co. Inc. | 1.92% | |
| 13 | PRGO Perrigo Co PLC | 1.92% | |
| 14 | EWTX Edgewise Therapeutics Inc | 1.92% | |
| 15 | TRVI Trevi Therapeutics Inc | 1.92% | |
| 16 | BMY Bristol Myers Squibb Co | 1.84% | |
| 17 | OCUL Ocular Therapeutix Inc | 1.83% | |
| 18 | HRMY Harmony Biosciences Holdings | 1.78% | |
| 19 | RPRX Royalty Pharma PLC | 1.76% | |
| 20 | JNJ Johnson + Johnson | 1.76% | |
| 21 | LGND Ligand Pharmaceuticals | 1.76% | |
| 22 | AMRX Amneal Pharmaceuticals Inc | 1.76% | |
| 23 | PCRX Pacira Biosciences Inc | 1.71% | |
| 24 | PFE Pfizer Inc | 1.69% | |
| 25 | JAZZ Jazz Pharmaceuticals PLC | 1.62% | |
| 26 | RAPP Rapport Therapeutics Inc | 1.62% | |
| 27 | VTRS Viatris Inc | 1.62% | |
| 28 | PBH Prestige Consumer Healthcare | 1.61% | |
| 29 | ELAN Elanco Animal Health Inc | 1.61% | |
| 30 | HROW Harrow Inc | 1.6% | |
| 31 | ANRO Alto Neuroscience Inc | 1.59% | |
| 32 | MAZE Maze Therapeutics Inc | 1.58% | |
| 33 | LQDA Liquidia Corp | 1.58% | |
| 34 | MANE Veradermics Inc | 1.58% | |
| 35 | PAHC Phibro Animal Health Corp | 1.56% | |
| 36 | OGN Organon + Co | 1.55% | |
| 37 | LLY Eli Lilly + Co | 1.54% | |
| 38 | XERS Xeris Biopharma Holdings Inc | 1.49% | |
| 39 | SUPN Supernus Pharmaceuticals Inc | 1.47% | |
| 40 | AMPH Amphastar Pharmaceuticals in | 1.46% | |
| 41 | ZTS Zoetis Inc | 1.41% | |
| 42 | INVA Innoviva Inc | 1.4% | |
| 43 | ARVN Arvinas Inc | 1.38% | |
| 44 | INDV Indivior Pharmaceuticals Inc | 1.38% | |
| 45 | ANIP Ani Pharmaceuticals Inc | 1.32% | |
| 46 | AXSM Axsome Therapeutics Inc | 1.27% | |
| 47 | WVE Wave Life Sciences Inc | 1.25% | |
| 48 | LBRX LB Pharmaceuticals Inc | 1.15% | |
| 49 | SEPN Septerna Inc | 1.07% | |
| 50 | CRMD Cormedix Inc | 1.07% | |
| 51 | ZVRA Zevra Therapeutics Inc | 1.07% | |
| 52 | COLL Collegium Pharmaceutical Inc | 1.02% | |
| 53 | ACRS Aclaris Therapeutics Inc | 0.99% | |
| 54 | AQST Aquestive Therapeutics Inc | 0.97% | |
| 55 | TBPH Theravance Biopharma Inc | 0.95% | |
| 56 | PHAT Phathom Pharmaceuticals Inc | 0.87% | |
| 57 | ALMS Alumis Inc | 0.85% | |
| 58 | FULC Fulcrum Therapeutics Inc | 0.71% | |
| 59 | EOLS Evolus Inc | 0.68% | |
| 60 | RLMD Relmada Therapeutics Inc | 0.66% | |
| 61 | LXRX Lexicon Pharmaceuticals Inc | 0.58% | |
| 62 | BIOA Bioage Labs Inc | 0.57% | |
| 63 | EYPT Eyepoint Inc | 0.56% |
Issuer file 1 day old on 2026-09-04, against a median of 1 across the funds with a page. Every one of the 63 positions with its weight is in the fund's JSON file. See which other ETFs hold AMLX, and at what weight.
What does XPH share with other funds?
The fund nearest to XPH is IHE: the two hold 37.9% of their weight in common, in the 55 companies both own, and 91.3% of XPH itself is also held there. No covered fund holds more than that in common with XPH; it duplicates nothing here closely.
| Fund | Overlap by weight | Of XPH held there | Of that fund in XPH | Companies in both | Overlap bar |
|---|---|---|---|---|---|
| IHE | 37.9% | 91.3% | 100.0% | 55 | |
| PJP | 32.2% | 32.2% | 67.0% | 19 | |
| PSCH | 17.6% | 25.5% | 24.1% | 16 | |
| PTH | 16.4% | 22.4% | 19.8% | 12 | |
| VHT | 11.2% | 89.2% | 33.5% | 55 | |
| RSPH | 11.2% | 11.8% | 11.2% | 7 | |
| IYH | 10.7% | 21.8% | 37.1% | 13 | |
| IBBQ | 9.8% | 69.5% | 9.8% | 44 | |
| XLV | 9.6% | 11.8% | 37.2% | 7 | |
| IXJ | 9.2% | 11.8% | 26.2% | 7 | |
| IBRN | 8.5% | 9.7% | 12.9% | 7 | |
| BMED | 8.3% | 11.5% | 14.3% | 6 |
From each issuer's latest file. Check XPH against any fund in the ETF overlap calculator · how overlap is measured.
What adds something different to XPH?
VDE shares 0% of weight with XPH and its weekly returns correlate with it at 0.17 over three years. The table lists the covered funds with the least in common with XPH, least shared weight first and, among equals, lowest correlation.
| Fund | Name | Overlap by weight | Correlation, 3y | Companies in both |
|---|---|---|---|---|
| VDE | Vanguard Energy ETF | 0.0% | 0.17 | 0 |
| VPU | Vanguard Utilities ETF | 0.0% | 0.27 | 0 |
| VDC | Vanguard Consumer Staples ETF | 0.0% | 0.38 | 0 |
| VOX | Vanguard Communication Services ETF | 0.0% | 0.44 | 0 |
| VPL | Vanguard FTSE Pacific ETF | 0.0% | 0.51 | 0 |
| VCR | Vanguard Consumer Discretionary ETF | 0.0% | 0.55 | 0 |
| VYMI | Vanguard International High Dividend Yield ETF | 0.0% | 0.58 | 0 |
| VIS | Vanguard Industrials ETF | 0.0% | 0.58 | 0 |
Cost, returns and risk
| Expense ratio | 0.35% |
|---|---|
| Dividend yield | 0.47% |
| Total return, 1 year | 49.2% |
| Total return, 3 years cumulative | 70.9% |
| Total return, 5 years cumulative | 57.1% |
| Volatility, annualised | 20.1% |
| Worst fall, 3 years | -21.1% |
| Beta against SPY, 3 years of weekly returns | 0.76 |
| Weight in the ten largest positions | 26.0% |
| Largest single position | 3.8% |
| Assets under management | $0.6B |
Expense ratio, yield and assets are reference data; every other figure is computed here from weekly closes.
How it moves with the market
| Against | Correlation, 3 years | Covariance, annualised, in percent squared |
|---|---|---|
| SPY | 0.54loosely linked | 158 |
| QQQ | 0.41loosely linked | 163 |
Weekly total returns. What the bands mean · why the covariance is printed.
Year by year
| Year | Total return |
|---|---|
| 2026 | 26.9% |
| 2025 | 31.6% |
| 2024 | 4.9% |
| 2023 | 3.0% |
| 2022 | -9.8% |
One year
Where to go next
- BMED, iShares Health Innovation Active ETF
- IBB, iShares Biotechnology ETF
- IBBQ, Invesco Nasdaq Biotechnology ETF
- IBRN, iShares Neuroscience and Healthcare ETF
- Run a portfolio x-ray to see what XPH carries once you look through it
- Compare XPH against any other fund in the builder
Holdings from the issuer file published 2026-09-03. Prices through 2026-09-04. How every figure here is produced. Measurements, not investment advice.
