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IBBQ holdings and overlap
What does IBBQ hold, as of its issuer file of 2026-09-05?
IBBQ holds 248 positions as of the issuer file dated 2026-09-05. The three largest are Amgen Inc at 8.84%, Vertex Pharmaceuticals Inc at 8.26% and Gilead Sciences Inc at 7.61%.
| Rank | Company | Weight | Weight bar |
|---|---|---|---|
| 1 | AMGN Amgen Inc | 8.84% | |
| 2 | VRTX Vertex Pharmaceuticals Inc | 8.26% | |
| 3 | GILD Gilead Sciences Inc | 7.61% | |
| 4 | REGN Regeneron Pharmaceuticals Inc | 5.51% | |
| 5 | MRNA Moderna Inc | 3.73% | |
| 6 | RVMD Revolution Medicines Inc | 2.88% | |
| 7 | ALNY Alnylam Pharmaceuticals Inc | 2.29% | |
| 8 | ILMN Illumina Inc | 2.13% | |
| 9 | BIIB Biogen Inc | 2.11% | |
| 10 | ARGX Argenx SE | 1.84% | |
| 11 | RPRX Royalty Pharma PLC | 1.84% | |
| 12 | INSM Insmed Inc | 1.77% | |
| 13 | INCY Incyte Corp | 1.63% | |
| 14 | ROIV Roivant Sciences Ltd | 1.62% | |
| 15 | GH Guardant Health Inc | 1.38% | |
| 16 | UTHR United Therapeutics Corp | 1.34% | |
| 17 | VTRS Viatris Inc | 1.28% | |
| 18 | MEDP Medpace Holdings Inc | 1.09% | |
| 19 | ASND Ascendis Pharma A/S | 1.07% | |
| 20 | NBIX Neurocrine Biosciences Inc | 1.01% | |
| 21 | JAZZ Jazz Pharmaceuticals PLC | 1.0% | |
| 22 | EXEL Exelixis Inc | 0.96% | |
| 23 | BBIO Bridgebio Pharma Inc | 0.95% | |
| 24 | SMMT Summit Therapeutics Inc | 0.88% | |
| 25 | HALO Halozyme Therapeutics Inc | 0.84% | |
| 26 | BMRN BioMarin Pharmaceutical Inc | 0.83% | |
| 27 | MDGL Madrigal Pharmaceuticals Inc | 0.8% | |
| 28 | ARWR Arrowhead Pharmaceuticals Inc | 0.78% | |
| 29 | BNTX BioNTech SE | 0.78% | |
| 30 | ONC BeOne Medicines Ltd | 0.76% | |
| 31 | TEM Tempus AI Inc | 0.73% | |
| 32 | AXSM Axsome Therapeutics Inc | 0.69% | |
| 33 | KRYS Krystal Biotech Inc | 0.68% | |
| 34 | SNY Sanofi SA | 0.66% | |
| 35 | CYTK Cytokinetics Inc | 0.64% | |
| 36 | PRAX Praxis Precision Medicines Inc | 0.63% | |
| 37 | KYMR Kymera Therapeutics Inc | 0.62% | |
| 38 | IONS Ionis Pharmaceuticals Inc | 0.62% | |
| 39 | PTGX Protagonist Therapeutics Inc | 0.6% | |
| 40 | PCVX Vaxcyte Inc | 0.57% | |
| 41 | IBRX ImmunityBio Inc | 0.55% | |
| 42 | IMVT Immunovant Inc | 0.52% | |
| 43 | TWST Twist Bioscience Corp | 0.5% | |
| 44 | SYRE Spyre Therapeutics Inc | 0.5% | |
| 45 | ALKS Alkermes PLC | 0.5% | |
| 46 | TXG 10X Genomics Inc | 0.47% | |
| 47 | CAI Caris Life Sciences Inc | 0.46% | |
| 48 | RYTM Rhythm Pharmaceuticals Inc | 0.45% | |
| 49 | ABVX Abivax SA | 0.43% | |
| 50 | SRRK Scholar Rock Holding Corp | 0.43% | |
| 51 | CGON CG oncology Inc | 0.42% | |
| 52 | MIRM Mirum Pharmaceuticals Inc | 0.4% | |
| 53 | TVTX Travere Therapeutics Inc | 0.39% | |
| 54 | COGT Cogent Biosciences Inc | 0.38% | |
| 55 | XENE Xenon Pharmaceuticals Inc | 0.37% | |
| 56 | PTCT PTC Therapeutics Inc | 0.37% | |
| 57 | LGND Ligand Pharmaceuticals Inc | 0.37% | |
| 58 | ORKA Oruka Therapeutics Inc | 0.36% | |
| 59 | AMRX Amneal Pharmaceuticals Inc | 0.36% | |
| 60 | CRSP CRISPR Therapeutics AG | 0.35% | |
| 61 | ERAS Erasca Inc | 0.32% | |
| 62 | ACAD ACADIA Pharmaceuticals Inc | 0.31% | |
| 63 | EWTX Edgewise Therapeutics Inc | 0.3% | |
| 64 | INDV Indivior Pharmaceuticals Inc | 0.27% | |
| 65 | DFTX Definium Therapeutics Inc | 0.27% | |
| 66 | RLAY Relay Therapeutics Inc | 0.26% | |
| 67 | DYN Dyne Therapeutics Inc | 0.26% | |
| 68 | IOVA Iovance Biotherapeutics Inc | 0.25% | |
| 69 | TARS Tarsus Pharmaceuticals Inc | 0.25% | |
| 70 | ADPT Adaptive Biotechnologies Corp | 0.25% | |
| 71 | AMLX Amylyx Pharmaceuticals Inc | 0.24% | |
| 72 | GPCR Structure Therapeutics Inc | 0.24% | |
| 73 | ELVN Enliven Therapeutics Inc | 0.23% | |
| 74 | KNSA Kiniksa Pharmaceuticals International Plc | 0.23% | |
| 75 | DNLI Denali Therapeutics Inc | 0.23% | |
| 76 | IDYA Ideaya Biosciences Inc | 0.22% | |
| 77 | ABCL AbCellera Biologics Inc | 0.22% | |
| 78 | GRAL GRAIL Inc | 0.22% | |
| 79 | VCYT Veracyte Inc | 0.22% | |
| 80 | TNGX Tango Therapeutics Inc | 0.21% | |
| 81 | BEAM Beam Therapeutics Inc | 0.2% | |
| 82 | IRON Disc Medicine Inc | 0.2% | |
| 83 | ARQT Arcutis Biotherapeutics Inc | 0.19% | |
| 84 | NAMS Newamsterdam Pharma Co NV | 0.19% | |
| 85 | MBX MBX Biosciences Inc | 0.19% | |
| 86 | QURE uniQure NV | 0.18% | |
| 87 | ATAI AtaiBeckley Inc | 0.18% | |
| 88 | NRIX Nurix Therapeutics Inc | 0.17% | |
| 89 | VERA Vera Therapeutics Inc | 0.17% | |
| 90 | GMAB Genmab A/S | 0.16% | |
| 91 | BCRX BioCryst Pharmaceuticals Inc | 0.16% | |
| 92 | PGEN Precigen Inc | 0.16% | |
| 93 | SUPN Supernus Pharmaceuticals Inc | 0.16% | |
| 94 | PHVS Pharvaris NV | 0.16% | |
| 95 | TRVI Trevi Therapeutics Inc | 0.16% | |
| 96 | HRMY Harmony Biosciences Holdings Inc | 0.16% | |
| 97 | SRPT Sarepta Therapeutics Inc | 0.15% | |
| 98 | OCUL Ocular Therapeutix Inc | 0.15% | |
| 99 | MLYS Mineralys Therapeutics Inc | 0.15% | |
| 100 | ADMA ADMA Biologics Inc | 0.14% |
Issuer file -1 days old on 2026-09-04, against a median of 1 across the funds with a page. Every one of the 248 positions with its weight is in the fund's JSON file. See which other ETFs hold AMGN, and at what weight.
What does IBBQ duplicate?
The fund nearest to IBBQ is IBB: the two hold 85.1% of their weight in common, in the 211 companies both own, and 90.8% of IBBQ itself is also held there. Owning IBBQ alongside the funds at the top of this table means holding mostly the same companies twice.
| Fund | Overlap by weight | Of IBBQ held there | Of that fund in IBBQ | Companies in both | Overlap bar |
|---|---|---|---|---|---|
| IBB | 85.1% | 90.8% | 92.9% | 211 | |
| XBI | 41.4% | 73.7% | 83.7% | 115 | |
| PBE | 37.8% | 49.0% | 87.0% | 26 | |
| BMED | 33.4% | 49.7% | 41.8% | 24 | |
| PTH | 23.9% | 24.0% | 71.2% | 35 | |
| PJP | 21.5% | 29.6% | 53.7% | 16 | |
| IDNA | 21.4% | 27.7% | 67.3% | 29 | |
| QQQJ | 19.1% | 25.4% | 19.1% | 19 | |
| IYH | 18.0% | 67.0% | 18.0% | 31 | |
| VHT | 17.7% | 88.8% | 17.7% | 186 | |
| IWO | 16.5% | 24.0% | 16.8% | 140 | |
| RSPH | 15.7% | 39.0% | 16.9% | 8 |
From each issuer's latest file. Check IBBQ against any fund in the ETF overlap calculator · how overlap is measured.
What adds something different to IBBQ?
VDE shares 0% of weight with IBBQ and its weekly returns correlate with it at 0.11 over three years. The table lists the covered funds with the least in common with IBBQ, least shared weight first and, among equals, lowest correlation.
| Fund | Name | Overlap by weight | Correlation, 3y | Companies in both |
|---|---|---|---|---|
| VDE | Vanguard Energy ETF | 0.0% | 0.11 | 0 |
| VPU | Vanguard Utilities ETF | 0.0% | 0.24 | 0 |
| VDC | Vanguard Consumer Staples ETF | 0.0% | 0.32 | 0 |
| SPLV | Invesco S&P 500 Low Volatility ETF | 0.0% | 0.42 | 0 |
| XLG | Invesco S&P 500 Top 50 ETF | 0.0% | 0.48 | 0 |
| VCR | Vanguard Consumer Discretionary ETF | 0.0% | 0.50 | 0 |
| VPL | Vanguard FTSE Pacific ETF | 0.0% | 0.52 | 0 |
| VIS | Vanguard Industrials ETF | 0.0% | 0.53 | 0 |
Cost, returns and risk
| Expense ratio | 0.19% |
|---|---|
| Dividend yield | 0.72% |
| Total return, 1 year | 50.3% |
| Total return, 3 years cumulative | 81.2% |
| Total return, 5 years cumulative | 39.6% |
| Volatility, annualised | 20.6% |
| Worst fall, 3 years | -20.1% |
| Beta against SPY, 3 years of weekly returns | 0.8 |
| Weight in the ten largest positions | 45.2% |
| Largest single position | 8.8% |
| Assets under management | $0.1B |
Expense ratio, yield and assets are reference data; every other figure is computed here from weekly closes.
How it moves with the market
| Against | Correlation, 3 years | Covariance, annualised, in percent squared |
|---|---|---|
| SPY | 0.56loosely linked | 166 |
| QQQ | 0.47loosely linked | 189 |
Weekly total returns. What the bands mean · why the covariance is printed.
Year by year
| Year | Total return |
|---|---|
| 2026 | 27.3% |
| 2025 | 33.3% |
| 2024 | -0.6% |
| 2023 | 4.7% |
| 2022 | -10.4% |
One year
Where to go next
- IBRN, iShares Neuroscience and Healthcare ETF
- IDNA, iShares Genomics Immunology and Healthcare ETF
- IHE, iShares U.S. Pharmaceuticals ETF
- IHF, iShares U.S. Healthcare Providers ETF
- Run a portfolio x-ray to see what IBBQ carries once you look through it
- Compare IBBQ against any other fund in the builder
Holdings from the issuer file published 2026-09-05. Prices through 2026-09-04. How every figure here is produced. Measurements, not investment advice.