IBRN holdings and overlap
iShares Neuroscience and Healthcare ETF (IBRN) holds 68 positions in its iShares file of 2026-10-27. Its three largest are Biogen (BIIB) at 5.47%, Alkermes (ALKS) at 4.60% and Neurocrine Biosciences (NBIX) at 4.49%, and its ten largest make up 41.6% of the fund.
In its iShares file of 2026-10-27, IBRN is 79.9% health care by sector (no sector found for 19.9%), with none of it in mega-cap tech or in the ten largest US companies by market value. By country, 71.4% of IBRN is in the United States, 4.1% in Belgium, 3.7% in Canada and 3.3% in South Korea.
What does IBRN hold, as of its issuer file of 2026-10-27?
Biogen is 5.47% of IBRN on its own, against a median largest position of 8.6% across the 28 Health Care funds with a page here. The position IBRN carries furthest above that group is Alkermes at 4.6% of the fund, a company the median fund in that group does not hold at all.
| Rank | Company | Weight | Weight bar |
|---|---|---|---|
| 1 | BIIB Biogen | 5.47% | |
| 2 | ALKS Alkermes | 4.6% | |
| 3 | NBIX Neurocrine Biosciences | 4.49% | |
| 4 | EWTX Edgewise Therapeutics | 4.38% | |
| 5 | PTCT PTC Therapeutics | 4.28% | |
| 6 | ARGX Argenx SE ADR | 4.09% | |
| 7 | SRRK Scholar Rock | 3.67% | |
| 8 | PRAX Praxis Precision Medicines | 3.63% | |
| 9 | DNTH Dianthus Therapeutics | 3.51% | |
| 10 | ACAD ACADIA Pharmaceuticals | 3.44% | |
| 11 | SUPN Supernus Pharmaceuticals | 3.37% | |
| 12 | 326030.KR SK Biopharmaceuticals Ltd | 3.35% | |
| 13 | DYN Dyne Therapeutics | 3.33% | |
| 14 | HLUNB.DK H. Lundbeck | 3.15% | |
| 15 | BHVN Biohaven | 2.96% | |
| 16 | AXGN Axogen | 2.96% | |
| 17 | XENE Xenon Pharmaceuticals | 2.88% | |
| 18 | SRPT Sarepta Therapeutics | 2.88% | |
| 19 | NEU.AU Neuren Pharmaceuticals | 2.18% | |
| 20 | BIOAB.SE Bioarctic | 2.04% | |
| 21 | 4588.JP Oncolys Biopharma Inc | 1.72% | |
| 22 | TSHA Taysha Gene Therapies | 1.69% | |
| 23 | LBRX LB Pharmaceuticals Inc | 1.58% | |
| 24 | IDIA.CH Idorsia N Ltd | 1.55% | |
| 25 | ANRO Alto Neuroscience | 1.24% | |
| 26 | RUBICON.IN Rubicon Research | 1.24% | |
| 27 | IART Integra LifeSciences | 1.2% | |
| 28 | RAPP Rapport Therapeutics | 1.19% | |
| 29 | APMD Apnimed Inc | 1.14% | |
| 30 | DYVOX.SE Dynavox Group | 1.09% | |
| 31 | MEDCL.FR Medincell SA | 1.06% | |
| 32 | CBLL Ceribell | 1.05% | |
| 33 | ANNX Annexon | 0.93% | |
| 34 | SLDB Solid Biosciences | 0.8% | |
| 35 | BWAY Brainsway ADR Representing Ltd | 0.65% | |
| 36 | NGNE Neurogene | 0.64% | |
| 37 | DRUG Bright Minds Biosciences | 0.62% | |
| 38 | OVID Ovid Therapeutics | 0.62% | |
| 39 | PRTA Prothena | 0.6% | |
| 40 | DSGN Design Therapeutics | 0.55% | |
| 41 | NPCE Neuropace | 0.54% | |
| 42 | 4592.JP Sanbio Ltd | 0.53% | |
| 43 | 7666.HK Metis Techbio | 0.53% | |
| 44 | 2190.HK Zylox-Tonbridge Medical Tech H | 0.5% | |
| 45 | CAPR Capricor Therapeutics | 0.49% | |
| 46 | BNTC Benitec Biopharma | 0.44% | |
| 47 | CLPT ClearPoint Neuro | 0.4% | |
| 48 | SANN.CH Santhera N AG | 0.37% | |
| 49 | 2172.HK Microport Neurotech Corp | 0.35% | |
| 50 | VNDA Vanda Pharmaceuticals | 0.35% | |
| 51 | ABEO Abeona Therapeutics | 0.34% | |
| 52 | KYTX Kyverna Therapeutics | 0.33% | |
| 53 | NWRN.CH Newron Pharmaceuticals | 0.29% | |
| 54 | ALEC Alector | 0.26% | |
| 55 | PEPG PepGen | 0.24% | |
| 56 | MOBI Mobia Medical Inc | 0.22% | |
| 57 | ABOS Acumen Pharmaceuticals | 0.21% | |
| 58 | CAMP Camp4 Therapeutics Corp | 0.2% | |
| 59 | NGEN NervGen Pharma | 0.19% | |
| 60 | AVXL Anavex Life Sciences | 0.18% | |
| 61 | LRMR Larimar Therapeutics | 0.17% | |
| 62 | TRDA Entrada Therapeutics | 0.16% | |
| 63 | MPLT Maplight Therapeutics | 0.14% | |
| 64 | TNXP Tonix Pharmaceuticals | 0.14% | |
| 65 | VYGR Voyager Therapeutics | 0.14% | |
| 66 | NERV Minerva Neurosciences | 0.13% | |
| 67 | CGTX Cognition Therapeutics | 0.1% | |
| 68 | NMRA Neumora Therapeutics | 0.04% |
The most recent file iShares has published for IBRN is dated 2026-10-27, 1 day before these prices, which is the median for the iShares ETFs covered here. Every one of the 68 positions IBRN holds, with its weight, is in the fund's JSON file. See the other 101 ETFs with a page here that hold BIIB, and how their weights compare with the 5.47% IBRN gives it.
Category: Health Care, set by TickerInside from the ETF's own latest file. In its file of 2026-10-27, 100% of its stocks whose sector is known are health care companies, each in the sector the site gives that company. How categories are set.
https://tickerinside.com/api/v1/fund/ibrn.jsonhttps://tickerinside.com/api/v1/fund/ibrn.csv=IMPORTDATA("https://tickerinside.com/api/v1/fund/ibrn.csv")If your sheet uses a decimal comma: =IMPORTDATA("https://tickerinside.com/api/v1/fund/ibrn.csv"; ","; "en_US")curl -s https://tickerinside.com/api/v1/fund/ibrn.jsonHow much money went into or out of IBRN?
On the close of Friday, October 23, 2026, IBRN neither created nor redeemed shares. Over its last 5 closes, a net inflow of $0.
From IBRN's own holdings files. Every ETF's latest flows.
How is IBRN split by sector and country?
| Sector | Weight | Weight bar |
|---|---|---|
| Health care | 79.9% | |
| No sector found | 19.9% |
| Country | Weight | Weight bar |
|---|---|---|
| United States | 71.4% | |
| Belgium | 4.1% | |
| Canada | 3.7% | |
| South Korea | 3.3% | |
| Denmark | 3.2% | |
| Sweden | 3.1% | |
| Japan | 2.2% | |
| Switzerland | 2.2% | |
| Australia | 2.2% | |
| Hong Kong | 1.4% | |
| Other countries | 2.9% |
From its iShares file of 2026-10-27. How these are measured.
What did IBRN hold in its SEC reports since 2022?
In IBRN's SEC filings, its largest position went from Prothena Corporation plc (PRTA) at 7.28% on 2022-10-31 to Dianthus Therapeutics, Inc. (DNTH) at 5.34% on 2026-07-31, across 16 quarterly reports.
| Report | Positions | Largest | Top 10 |
|---|---|---|---|
| 2022-10-31 | 38 | PRTA 7.28% | 45.7% |
| 2023-10-31 | 44 | NBIX 4.74% | 43.8% |
| 2024-10-31 | 56 | BHVN 4.87% | 40.1% |
| 2025-10-31 | 58 | PRAX 5.82% | 39.6% |
| 2026-07-31 | 65 | DNTH 5.34% | 45.4% |
The first report, then the last of each year, of the 16 reports IBRN filed on SEC Form N-PORT from 2022-10-31 to 2026-07-31, each company under its ticker today. Every position of every report is in its quarterly file, and at any date at /api/v1/history/ibrn/{date}.json. How these are read.
What does IBRN share with other ETFs?
The ETF nearest to IBRN is FBT: the two hold 16.6% of their weight in common, in the 5 companies both own, and 21.6% of IBRN itself is also held there. IBRN barely overlaps any covered ETF.
| ETF | Overlap by weight | Of IBRN held there | Of that ETF in IBRN | Companies in both | Overlap bar |
|---|---|---|---|---|---|
| FBT | 16.6% | 21.6% | 16.6% | 5 | |
| PBE | 14.6% | 20.6% | 14.8% | 5 | |
| XBI | 12.3% | 49.0% | 12.3% | 20 | |
| PSCH | 10.5% | 19.8% | 10.5% | 6 | |
| IBB | 10.2% | 59.5% | 10.2% | 29 | |
| BBH | 9.8% | 14.1% | 10.7% | 3 | |
| BMED | 8.5% | 26.5% | 9.0% | 6 | |
| IBBQ | 8.3% | 58.6% | 8.3% | 28 | |
| XPH | 7.6% | 11.8% | 7.6% | 5 | |
| PTH | 6.0% | 12.1% | 6.1% | 4 | |
| FMED | 6.0% | 15.1% | 6.0% | 5 | |
| XHE | 4.1% | 6.2% | 4.4% | 5 |
FBT's holdings are from its SEC Form N-PORT for the period ended 2026-06-30, filed 2026-08-21. BBH's holdings are from its SEC Form N-PORT for the period ended 2026-06-30, filed 2026-08-26. FMED's holdings are from its SEC Form N-PORT for the period ended 2026-08-31, filed 2026-10-26. The other ETFs' holdings are from their issuers' latest files. Check IBRN against any ETF in the ETF overlap calculator · how overlap is measured.
What adds something different to IBRN?
RING shares 0% of weight with IBRN and its weekly returns correlate with it at 0.31 over three years. The table lists the covered ETFs with the least in common with IBRN, least shared weight first and, among equals, lowest correlation.
| ETF | Name | Overlap by weight | Correlation, 3y | Companies in both |
|---|---|---|---|---|
| RING | iShares MSCI Global Gold Miners ETF | 0.0% | 0.31 | 0 |
| SOXX | iShares Semiconductor ETF | 0.0% | 0.45 | 0 |
| IYR | iShares U.S. Real Estate ETF | 0.0% | 0.48 | 0 |
| USRT | iShares Core U.S. REIT ETF | 0.0% | 0.49 | 0 |
| PICK | iShares MSCI Global Metals & Mining Producers ETF | 0.0% | 0.51 | 0 |
| REET | iShares Global REIT ETF | 0.0% | 0.52 | 0 |
| OEF | iShares S&P 100 ETF | 0.0% | 0.53 | 0 |
| QUAL | iShares MSCI USA Quality Factor ETF | 0.0% | 0.56 | 0 |
Cost, returns and risk
| Expense ratio | 0.47% |
|---|---|
| Dividend yield | 0.96% |
| Total return, 1 year | 10.0% |
| Total return, 3 years cumulative | 59.8% |
| Total return, 5 years cumulative | n/a |
| Volatility, annualised | 26.3% |
| Worst fall, 3 years | -31.4% |
| Beta against SPY, 3 years of weekly returns | 1.1 |
| Weight in the ten largest positions | 41.6% |
| Largest single position | 5.5% |
Expense ratio, yield and assets are reference data (the expense ratio from IBRN's SEC filing of 2025-11-21); the weight in the ten largest positions and the largest single position are from the issuer file of 2026-10-27; every other figure is computed here from weekly closes.
How it moves with the market
| Against | Correlation, 3 years | Covariance, annualised, in percent squared |
|---|---|---|
| SPY | 0.58loosely linked | 212 |
| QQQ | 0.51loosely linked | 258 |
Weekly total returns. What the bands mean · why the covariance is printed.
Year by year
| Year | Total return |
|---|---|
| 2026 | 1.9% |
| 2025 | 28.5% |
| 2024 | -2.8% |
| 2023 | 0.9% |
One year
Where to go next
- IDNA, iShares Genomics Immunology and Healthcare ETF
- IHE, iShares U.S. Pharmaceuticals ETF
- IHF, iShares U.S. Healthcare Providers ETF
- IHI, iShares U.S. Medical Devices ETF
- Run a portfolio x-ray to see what IBRN carries once you look through it
- Compare IBRN against any other ETF in the builder
Holdings from the most recent file iShares has published, dated 2026-10-27. Prices through 2026-10-28. How every figure here is produced. Measurements, not investment advice.
Cite this page
TickerInside, iShares Neuroscience and Healthcare ETF (IBRN), holdings from the issuer's file of 2026-10-27, https://tickerinside.com/etf/ibrn/, CC BY 4.0
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