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PBE holdings and overlap
What does PBE hold, as of its issuer file of 2026-09-05?
PBE holds 30 positions as of the issuer file dated 2026-09-05. The three largest are Royalty Pharma PLC at 5.22%, Gilead Sciences Inc at 5.13% and Biogen Inc at 5.05%.
| Rank | Company | Weight | Weight bar |
|---|---|---|---|
| 1 | RPRX Royalty Pharma PLC | 5.22% | |
| 2 | GILD Gilead Sciences Inc | 5.13% | |
| 3 | BIIB Biogen Inc | 5.05% | |
| 4 | AMGN Amgen Inc | 5.02% | |
| 5 | REGN Regeneron Pharmaceuticals Inc | 5.02% | |
| 6 | VRTX Vertex Pharmaceuticals Inc | 4.99% | |
| 7 | NTRA Natera Inc | 4.92% | |
| 8 | ILMN Illumina Inc | 4.9% | |
| 9 | SRPT Sarepta Therapeutics Inc | 3.28% | |
| 10 | NVAX Novavax Inc | 2.98% | |
| 11 | EXEL Exelixis Inc | 2.87% | |
| 12 | NBIX Neurocrine Biosciences Inc | 2.8% | |
| 13 | BCRX BioCryst Pharmaceuticals Inc | 2.79% | |
| 14 | LEGN Legend Biotech Corp | 2.78% | |
| 15 | TGTX TG Therapeutics Inc | 2.78% | |
| 16 | HALO Halozyme Therapeutics Inc | 2.78% | |
| 17 | BMRN BioMarin Pharmaceutical Inc | 2.77% | |
| 18 | ARDX Ardelyx Inc | 2.75% | |
| 19 | QGEN Qiagen NV | 2.74% | |
| 20 | INCY Incyte Corp | 2.69% | |
| 21 | ANAB AnaptysBio Inc | 2.68% | |
| 22 | PTGX Protagonist Therapeutics Inc | 2.67% | |
| 23 | VCYT Veracyte Inc | 2.66% | |
| 24 | PTCT PTC Therapeutics Inc | 2.6% | |
| 25 | UTHR United Therapeutics Corp | 2.59% | |
| 26 | VCEL Vericel Corp | 2.56% | |
| 27 | RGEN Repligen Corp | 2.54% | |
| 28 | ACAD ACADIA Pharmaceuticals Inc | 2.52% | |
| 29 | MRNA Moderna Inc | 2.52% | |
| 30 | COLL Collegium Pharmaceutical Inc | 2.36% |
Issuer file -1 days old on 2026-09-04, against a median of 1 across the funds with a page. Every one of the 30 positions with its weight is in the fund's JSON file. See which other ETFs hold RPRX, and at what weight.
What does PBE share with other funds?
The fund nearest to PBE is IBB: the two hold 40.6% of their weight in common, in the 25 companies both own, and 84.1% of PBE itself is also held there. No covered fund holds more than that in common with PBE; it duplicates nothing here closely.
| Fund | Overlap by weight | Of PBE held there | Of that fund in PBE | Companies in both | Overlap bar |
|---|---|---|---|---|---|
| IBB | 40.6% | 84.1% | 52.0% | 25 | |
| IBBQ | 37.8% | 87.0% | 49.0% | 26 | |
| BMED | 27.6% | 41.3% | 29.6% | 11 | |
| XBI | 24.9% | 79.4% | 25.4% | 24 | |
| PJP | 21.2% | 25.2% | 22.4% | 6 | |
| IDNA | 17.1% | 21.1% | 25.2% | 6 | |
| IYH | 14.8% | 64.6% | 14.9% | 17 | |
| IBRN | 14.5% | 16.3% | 18.7% | 5 | |
| PSCH | 14.3% | 21.4% | 17.4% | 8 | |
| RSPH | 13.3% | 30.4% | 15.4% | 7 | |
| XLV | 12.2% | 30.4% | 12.2% | 7 | |
| VHT | 11.9% | 89.2% | 11.9% | 27 |
From each issuer's latest file. Check PBE against any fund in the ETF overlap calculator · how overlap is measured.
What adds something different to PBE?
VDE shares 0% of weight with PBE and its weekly returns correlate with it at 0.14 over three years. The table lists the covered funds with the least in common with PBE, least shared weight first and, among equals, lowest correlation.
| Fund | Name | Overlap by weight | Correlation, 3y | Companies in both |
|---|---|---|---|---|
| VDE | Vanguard Energy ETF | 0.0% | 0.14 | 0 |
| VPU | Vanguard Utilities ETF | 0.0% | 0.22 | 0 |
| VDC | Vanguard Consumer Staples ETF | 0.0% | 0.29 | 0 |
| XLG | Invesco S&P 500 Top 50 ETF | 0.0% | 0.45 | 0 |
| VPL | Vanguard FTSE Pacific ETF | 0.0% | 0.50 | 0 |
| VGK | Vanguard FTSE Europe ETF | 0.0% | 0.52 | 0 |
| VYMI | Vanguard International High Dividend Yield ETF | 0.0% | 0.52 | 0 |
| VOT | Vanguard Morningstar Mid-Cap Growth ETF | 0.0% | 0.57 | 0 |
Cost, returns and risk
| Expense ratio | 0.58% |
|---|---|
| Dividend yield | 1.60% |
| Total return, 1 year | 40.2% |
| Total return, 3 years cumulative | 66.6% |
| Total return, 5 years cumulative | 29.6% |
| Volatility, annualised | 19.6% |
| Worst fall, 3 years | -19.0% |
| Beta against SPY, 3 years of weekly returns | 0.75 |
| Weight in the ten largest positions | 46.5% |
| Largest single position | 5.2% |
| Assets under management | $0.5B |
Expense ratio, yield and assets are reference data; every other figure is computed here from weekly closes.
How it moves with the market
| Against | Correlation, 3 years | Covariance, annualised, in percent squared |
|---|---|---|
| SPY | 0.55loosely linked | 156 |
| QQQ | 0.46loosely linked | 176 |
Weekly total returns. What the bands mean · why the covariance is printed.
Year by year
| Year | Total return |
|---|---|
| 2026 | 20.1% |
| 2025 | 24.8% |
| 2024 | 1.1% |
| 2023 | 3.7% |
| 2022 | -10.8% |
One year
Where to go next
- PJP, Invesco Pharmaceuticals ETF
- PSCH, Invesco S&P SmallCap Health Care ETF
- PTH, Invesco Dorsey Wright Healthcare Momentum ETF
- RSPH, Invesco S&P 500 Equal Weight Health Care ETF
- Run a portfolio x-ray to see what PBE carries once you look through it
- Compare PBE against any other fund in the builder
Holdings from the issuer file published 2026-09-05. Prices through 2026-09-04. How every figure here is produced. Measurements, not investment advice.