Which ETFs hold Twist Bioscience (TWST)?

82 US stock ETFs hold Twist Bioscience (TWST). ARKG gives TWST the largest weight, 7.73% (SEC filing for the period ended 2026-07-31).

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TWSTTwist Bioscience$9B market cap, beta 2.19, held by 82 US stock ETFs
Last close, 2026-10-13
$151.33 -0.35%
52-week range 25 to 205
Stock ETFs holding it
82
25 in issuer files, 57 in SEC filings; 11 other ETFs listed apart
Largest weight
7.73% of that ETF, SEC filing for the period ended 2026-07-31
1 year
+437.4%
total return
3 years
+803.5%
worst fall -56.4%, volatility 78.5%
5 years
+28.9%
cumulative

TWST is the single largest position in 4 of them: WDNA, FRTY, HAPS and KOMP. The median weight across the 82 holders is 0.24%: 4 of them carry it above 5% and 64 keep it under 1%. Of the 311 covered funds with 500 or more positions, 45 hold TWST, at weights from under 0.01% to 1.59%.

Over three years TWST returned 803.5%, with a worst fall of 56.4% and annualised volatility of 78.5%; its beta against SPY over the same weeks is 2.19. Its best calendar year in the data is 2026 at +377.1% and its worst 2022 at -69.2%.

Is TWST in VOO, SPY, IVV, QQQ, VTI, SCHD, IBB, XBI or FHLC?

TWST is in 4 of these 9 funds; XBI gives it the most weight, 1.74% (SPDR file of 2026-10-15), and VOO, SPY, IVV, QQQ and SCHD do not hold it.

ETFNameWeightRank in the ETFHoldings dated
VOOVanguard S&P 500 ETFnot held504 positionsSEC filing, 2026-06-30
SPYSPDR S&P 500 ETF Trustnot held504 positionsSPDR file, 2026-10-15
IVViShares Core S&P 500 ETFnot held505 positionsiShares file, 2026-10-15
QQQInvesco QQQ Trustnot held101 positionsInvesco file, 2026-10-15
VTIVanguard Total Stock Market ETF0.01%#892 of 3483SEC filing, 2026-06-30
SCHDSchwab US Dividend Equity ETFnot held99 positionsSEC filing, 2026-05-31
IBBiShares Biotechnology ETF0.66%#30 of 237iShares file, 2026-10-15
XBISPDR S&P Biotech ETF1.74%#3 of 159SPDR file, 2026-10-15
FHLCFidelity MSCI Health Care Index ETF0.07%#112 of 333SEC filing, 2026-07-31

Which ETFs hold TWST in their issuer files, and at what weight?

25 funds report TWST in their own issuer files, dated 2026-10-01 to 2026-10-16; GNOM gives it the most weight, 6.05%.

RankETFNameWeightIssuer file
1 GNOM Global X Genomics & Biotechnology ETF 6.05% 2026-10-16
2 IDNA iShares Genomics Immunology and Healthcare ETF 5.82% 2026-10-15
3 PTH Invesco Dorsey Wright Healthcare Momentum ETF 2.92% 2026-10-15
4 XBI SPDR S&P Biotech ETF 1.74% 2026-10-15
5 KOMP State Street SPDR S&P Kensho New Economies Composite ETF 1.59% 2026-10-15
6 DWAS Invesco Dorsey Wright SmallCap Momentum ETF 0.78% 2026-10-15
7 IBB iShares Biotechnology ETF 0.66% 2026-10-15
8 IWO iShares Russell 2000 Growth ETF 0.65% 2026-10-15
9 IBBQ Invesco Nasdaq Biotechnology ETF 0.64% 2026-10-15
10 IWM iShares Russell 2000 ETF 0.32% 2026-10-15
11 IWMW iShares IWM Premium Income+ ETF 0.32% 2026-10-15
12 RSSL Global X Russell 2000 ETF 0.30% 2026-10-16
13 ISCG iShares Morningstar Small-Cap Growth ETF 0.29% 2026-10-15
14 OMFS Invesco Russell 2000 Dynamic Multifactor ETF 0.25% 2026-10-15
15 SMLF iShares U.S. Small-Cap Equity Factor ETF 0.24% 2026-10-15
16 ISCB iShares Morningstar Small-Cap ETF 0.19% 2026-10-01
17 PRFZ Invesco RAFI US 1500 Small-Mid ETF 0.18% 2026-10-15
18 TECB iShares U.S. Tech Breakthrough Multisector ETF 0.16% 2026-10-15
19 ESML iShares ESG Aware MSCI USA Small-Cap ETF 0.14% 2026-10-15
20 SMMD iShares Russell 2500 ETF 0.13% 2026-10-15
21 MSML iShares MSCI USA Small-Cap ETF 0.13% 2026-10-15
22 WSML iShares MSCI World Small-Cap ETF 0.08% 2026-10-15
23 SPGM State Street SPDR Portfolio MSCI Global Stock Market ETF 0.02% 2026-10-15
24 ITOT iShares Core S&P Total U.S. Stock Market ETF 0.01% 2026-10-15
25 IWV iShares Russell 3000 ETF 0.01% 2026-10-15

Each of these 25 rows is dated by its issuer's own file, published on the issuer's schedule; the same 25 rows, in the same order, are in the JSON file for TWST and in the holders index. Look TWST up with an amount to see what a position in each ETF holds of it in dollars.

Use this data
JSONhttps://tickerinside.com/api/v1/sec/twst.json
CSVhttps://tickerinside.com/api/v1/sec/twst.csv
Sheets=IMPORTDATA("https://tickerinside.com/api/v1/sec/twst.csv")If your sheet uses a decimal comma: =IMPORTDATA("https://tickerinside.com/api/v1/sec/twst.csv"; ","; "en_US")
curlcurl -s https://tickerinside.com/api/v1/sec/twst.json
API reference · spreadsheet guide Add TickerInside to Claude to ask about TWST with this data

Which ETFs hold TWST in their latest SEC filing?

57 funds hold TWST in their latest Form N-PORT filing with the SEC, for periods ended 2026-05-31 to 2026-07-31; ARKG gives it the most weight, 7.73%.

ETFNameWeightPeriod of the filing
ARKGARK Genomic Revolution ETF7.73%2026-07-31
WDNAWisdomTree BioRevolution Fund5.95%2026-06-30
FRTYAlger Mid Cap 40 ETF4.79%2026-06-30
ARKKARK Innovation ETF3.31%2026-07-31
HAPSHarbor Human Capital Factor US Small Cap ETF2.86%2026-07-31
HELXFranklin Genomic Advancements ETF2.85%2026-06-30
HTECROBO Global Healthcare Technology and Innovation ETF2.23%2026-07-31
EKGFirst Trust Nasdaq Lux Digital Health Solutions ETF2.08%2026-06-30
GNMXCorgi Genomics & Precision Medicine ETF2.05%2026-06-30
PCSGPolen 5Perspectives Small-Mid Growth ETF1.78%2026-07-31
TSMEThrivent Small-Mid Cap Equity ETF1.38%2026-06-30
LFSCF/m Emerald Life Sciences Innovation ETF1.14%2026-05-31
FTXHFirst Trust Nasdaq Pharmaceuticals ETF1.03%2026-06-30
SCDSJPMorgan Fundamental Data Science Small Core ETF0.82%2026-06-30
MMSCFirst Trust Multi-Manager Small Cap Opportunities ETF0.79%2026-05-31
SGRWHarbor Active Small Cap Growth ETF0.63%2026-07-31
JSMLJanus Henderson Small Cap Growth Alpha ETF0.61%2026-07-31
FYCFirst Trust Small Cap Growth AlphaDEX Fund0.60%2026-07-31
ESSCEventide Small Cap ETF0.45%2026-07-31
FSEGFidelity Enhanced Small Cap Growth ETF0.40%2026-06-30
FYXFirst Trust Small Cap Core AlphaDEX Fund0.28%2026-07-31
TNXTT. Rowe Price Innovation Leaders ETF0.27%2026-06-30
FESMFidelity Enhanced Small Cap Core ETF0.26%2026-06-30
PWSPacer WealthShield ETF0.26%2026-07-31
STXKStrive Small-Cap ETF0.25%2026-06-30
BKSEBNY Mellon US Small Cap Core Equity ETF0.24%2026-07-31
ISMDInspire Small/Mid Cap ETF0.24%2026-05-31
FFSMFidelity Fundamental Small-Mid Cap ETF0.24%2026-07-31
VTWGVanguard Russell 2000 Growth ETF0.23%2026-05-31
KBFRInnovator U.S. Small Cap Managed 10 Buffer ETF0.22%2026-07-31
BBSCJPMorgan BetaBuilders U.S. Small Cap Equity ETF0.22%2026-07-31
RFLRInnovator U.S. Small Cap Managed Floor ETF0.20%2026-07-31
RESMColumbia Research Enhanced Small Cap ETF0.19%2026-06-30
WCEOHypatia Women CEO ETF0.17%2026-07-31
VBKVanguard Morningstar Small-Cap Growth ETF0.17%2026-06-30
FFFFounders 100 ETF0.14%2026-06-30
FADFirst Trust Multi Cap Growth AlphaDEX Fund0.12%2026-07-31
VTWOVanguard Russell 2000 ETF0.12%2026-05-31
GINNGoldman Sachs Innovate Equity ETF0.09%2026-05-31
SCHASchwab U.S. Small-Cap ETF0.09%2026-05-31
VXFVanguard Extended Market ETF0.08%2026-06-30
FHLCFidelity MSCI Health Care Index ETF0.07%2026-07-31
VBVanguard Small-Cap ETF0.07%2026-06-30
VHTVanguard Health Care ETF0.06%2026-05-31
GSSCGoldman Sachs ActiveBeta(R) U.S. Small Cap Equity ETF0.05%2026-05-31
DFASDimensional U.S. Small Cap ETF0.04%2026-07-31
MSSMMorgan Stanley Pathway Small-Mid Cap Equity ETF0.02%2026-05-31
ONEQFidelity Nasdaq Composite Index ETF0.01%2026-05-31
DFACDimensional U.S. Core Equity 2 ETF0.01%2026-07-31
TILTFlexShares Morningstar US Market Factor Tilt Index Fund0.01%2026-07-31
VTIVanguard Total Stock Market ETF0.01%2026-06-30
GTPEGoldman Sachs MSCI World Private Equity Return Tracker ETF0.01%2026-05-31
ESGVVanguard ESG U.S. Stock ETF0.01%2026-05-31
SCHBSchwab U.S. Broad Market ETF0.01%2026-05-31
VTHRVanguard Russell 3000 ETF0.01%2026-05-31
VTVanguard Total World Stock ETFunder 0.01%2026-07-31
AVTMAvantis Total Equity Markets ETFunder 0.01%2026-05-31

Each of the 57 dates is the end of the period a holder of TWST reported in its Form N-PORT filing, and opens that filing on EDGAR, the SEC's public archive. The same rows are under holders_sec_nport in the JSON file for TWST.

How many ETFs held TWST each year since 2019?

76 of today's US stock ETFs held TWST in their SEC reports for the second quarter of 2026, against 20 for the fourth quarter of 2019.

ETFs holding it, Q2 2026
76
in their SEC reports
ETFs holding it, Q4 2019
20
the same ETFs, 2019
Since Q4 2019
+56
ETFs holding it
Largest weight, Q2 2026
8.99% of the ETF
QuarterETFsBarLargest weight
Q4 201920DWAS 0.31%
Q4 202043XOVR 5.66%
Q4 202151ARKG 3.63%
Q4 202250ARKG 3.28%
Q4 202355WDNA 3.29%
Q4 202468ARKG 8.35%
Q4 202561ARKG 5.29%
Q2 202676ARKG 8.99%

TWST in the SEC reports (Form N-PORT) of today's US stock ETFs, Q4 2019 to Q2 2026, every quarter in its file. How these are counted.

Which other ETFs hold TWST outright?

Seven derivative-based funds and four funds read from their sponsors' files hold TWST outright in SEC filings and sponsors' files dated 2026-05-31 to 2026-10-16; HLTH gives it the most weight, 4.82%. None of them is counted among the 82 US stock ETFs above.

ETFNameKind of ETFHeld outrightHoldings dated
HLTHTema Healthcare AI ETFSponsor's file4.82%Tema file, 2026-10-16
CTAGCalamos Timpani Active SMID Growth ETFSponsor's file1.38%Calamos file, 2026-10-15
AESGHarbor AlphaEdge Small Cap Growth ETFSponsor's file1.10%Harbor file, 2026-10-15
LABUDirexion Daily S&P Biotech Bull 3X SharesDerivative-based0.92%SEC filing, 2026-07-31
AESBHarbor AlphaEdge Small Cap Core ETFSponsor's file0.70%Harbor file, 2026-10-15
BIBProShares Ultra Nasdaq BiotechnologyDerivative-based0.21%SEC filing, 2026-05-31
RBProShares Russell 2000 Dynamic Buffer ETFDerivative-based0.10%SEC filing, 2026-05-31
ITWOProShares Russell 2000 High Income ETFDerivative-based0.10%SEC filing, 2026-05-31
UWMProShares Ultra Russell2000Derivative-based0.06%SEC filing, 2026-05-31
URTYProShares UltraPro Russell2000Derivative-based0.04%SEC filing, 2026-05-31
HDGProShares Hedge Replication ETFDerivative-based0.02%SEC filing, 2026-05-31

How the ETFs listed apart are read.

What did $100 in TWST become over three years?

TWST ended at $903 after 156 weekly closes through 2026-10-16; the dashed line is the $100 put in.

How has TWST done, year by year?

YearTotal return
2026+377.1%
2025-31.7%
2024+26.1%
2023+54.8%
2022-69.2%

Returns and risk

Total return, 1 year437.4%
Total return, 3 years cumulative803.5%
Total return, 5 years cumulative28.9%
Volatility, annualised78.5%
Worst fall, 3 years-56.4%
Beta against SPY, 3 years of weekly returns2.19
Market cap$8.8B
Dividend yield0.00%
US stock ETFs holding it82
Broad ETFs holding it, 500 positions or more45 of 311

Market cap, price to earnings and yield are reference data; every other figure is computed here from 156 weekly closes.

What would diversify TWST?

The stocks that have moved least like TWST over the last 104 weeks, among those held by ten or more covered ETFs: CBOE correlates with it at -0.22 and TPB at -0.18, a measurement of co-movement rather than a suggestion.

TickerNameCorrelation, 104 weeks
CBOECboe Global Markets-0.22moves the opposite way
TPBTurning Point Brands, Inc.-0.18moves the opposite way
NFGNational Fuel Gas Company-0.17moves the opposite way
PMPhilip Morris International-0.17moves the opposite way
OXYOccidental Petroleum-0.17moves the opposite way
SUSuncor Energy Inc.-0.17moves the opposite way

What moves with TWST?

The other end of the same ranking: RGEN has moved with TWST at 0.60, MLAB at 0.57. Each row opens the pair side by side.

TickerNameCorrelation, 104 weeks
RGENRepligen Corporation0.60loosely linked
MLABMesa Laboratories, Inc.0.57loosely linked
SDGRSchrodinger, Inc.0.57loosely linked
TECHBio-Techne0.55loosely linked
AZTAAzenta, Inc.0.55loosely linked
GFFGriffon Corporation0.53loosely linked

Weekly total returns, among stocks held by ten or more covered ETFs; closed-end funds are left out of both tables. What the bands mean.

Which ETF has the largest weight in TWST?

ARKG, at 7.73% in its SEC filing for the period ended 2026-07-31, where TWST is position #2 of 32, followed by GNOM at 6.05% and WDNA at 5.95%.

ETFNameWeightRank in the ETFPositionsHoldings dated
ARKG ARK Genomic Revolution ETF 7.73% #2 32 SEC filing, 2026-07-31
GNOM Global X Genomics & Biotechnology ETF 6.05% #3 50 issuer file, 2026-10-16
WDNA WisdomTree BioRevolution Fund 5.95% #1 80 SEC filing, 2026-06-30
IDNA iShares Genomics Immunology and Healthcare ETF 5.82% #2 47 issuer file, 2026-10-15
FRTY Alger Mid Cap 40 ETF 4.79% #1 40 SEC filing, 2026-06-30
ARKK ARK Innovation ETF 3.31% #10 44 SEC filing, 2026-07-31
PTH Invesco Dorsey Wright Healthcare Momentum ETF 2.92% #9 52 issuer file, 2026-10-15
HAPS Harbor Human Capital Factor US Small Cap ETF 2.86% #1 195 SEC filing, 2026-07-31
HELX Franklin Genomic Advancements ETF 2.85% #9 61 SEC filing, 2026-06-30
HTEC ROBO Global Healthcare Technology and Innovation ETF 2.23% #4 62 SEC filing, 2026-07-31

An ETF page opens on every ticker that has one; the others open the fund's JSON file, with its holdings and the date of its issuer file or SEC filing. Run a portfolio x-ray to see how much TWST you hold across every ETF you own.

TWST weights from 25 issuer files, dated 2026-10-01 to 2026-10-16, and 57 SEC filings for periods ended 2026-05-31 to 2026-07-31. Prices through 2026-10-16. How every figure here is produced. Measurements, not investment advice.

Cite this page

TickerInside, Twist Bioscience (TWST), holders from each covered fund's own file and from SEC Form N-PORT filings, each dated, prices through 2026-10-16, https://tickerinside.com/stock/twst/, CC BY 4.0

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